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News

Knee pain and nerve pathways

Oxford researchers to redefine new human-based research models of pain

Professor Tonia Vincent is part of an interdisciplinary team from Oxford University leading a major new initiative which aims to redefine human-based research models for greater understanding of disease and the acceleration of new medicines.

Oxford scientists map the cells that drive Crohn’s disease fistulas

Researchers at the MRC Translational Immune Discovery Unit have identified how rare populations of abnormal cells drive the formation and persistence of fistulas - painful, tunnel-like tracts that develop in around 30% of people with Crohn’s disease - paving the way for targeted treatments.

Ignacio Melero receiving his award

Dr Ignacio Melero recognised for global contribution to advances in cancer immunotherapy

The Society for Immunotherapy of Cancer (SITC) has honoured Dr Ignacio (Nacho) Melero, Professor of Immunotherapy at NDM's Centre for Immuno-Oncology at Oxford, for his pioneering research transforming cancer treatment through immunotherapy.

Detailed map of the genome 1 pixel per nucleotide

Oxford scientists capture genome’s structure in unprecedented detail

Radcliff Department of Medicine scientists have achieved the most detailed view yet of how DNA folds and functions inside living cells, revealing the physical structures that control when and how genes are switched on.

Microbiome with microbiota

New Microbiome Innovation Network to drive UK Bioscience Research

Researchers from the Kennedy Institute are part of a UK-wide consortium that has been awarded a £644K BBSRC Network Grant to establish the Microbiome Innovation Network (Microbiome-Net).

Abdullah Khan receives Wellcome Career Development Award

Congratulations are in order for Dr Abdullah (Abs) Khan, who has been awarded a Wellcome Career Development Award for his research on age-related immune dysfunction using human model systems.

Oxford Oncology at ESMO 2025

Members of the Department of Oncology attended ESMO earlier this month to present their research, chair sessions, and network with collaborators from across Europe and beyond. Read the highlights from our department’s contributions to ESMO 2025.

Podcast: Regulatory T cell therapy in kidney transplants

A conversation with Fadi Issa about his recent article on regulatory T cell therapy in kidney transplants.

Major investment puts UK universities at the forefront of groundbreaking lymph node research

Three UK universities have been granted over £1.7m by the Medical Research Council (MRC) to establish a network of lymph node research centres across the UK. The novel LEGACY IIII Network (Lymph nodE single cell Genomics AnCestrY immunity, infection, inflammation and immunisation) will be co-led by the Universities of Oxford, Cardiff and Newcastle and will establish ten specialist lymph node research centres across the country.

A skeleton wearing a conference T-shirt

Unravelling T-Cell Recognition: Insights from Immunology and AI

From 29 September to 1 October 2025, researchers from across the world gathered in Oxford for a unique conference and hackathon exploring how advances in artificial intelligence can deepen understanding of T-cell biology.

Prof Calliope Dendrou, alongside 2025 Nobel Prize Winner, aims to ‘stop the clock’ on chronic inflammation

Teaming up with scientists and clinician-scientists at the University of Birmingham, and with 2025 Nobel Prize winner Professor Shimon Sakaguchi from Osaka University, Professor Calliope Dendrou from the Kennedy Institute will work on a major research programme to transform the treatment of autoimmune diseases by halting chronic inflammation at its source.

NDM scientists receive funding for children’s cancer vaccine development

A new partnership between Alice’s Arc, the Centre for Immuno-Oncology in the Nuffield Department of Medicine and the Sir William Dunn School of Pathology will pioneer the development of a bespoke mRNA vaccine to improve treatment outcomes for children with rhabdomyosarcoma, a rare and aggressive form of soft tissue cancer.

New research finds T cells linked to mild COVID-19 and future protection

A new study, led by researchers at the CAMS Oxford Institute in the Nuffield Department of Medicine and TIDU in the MRC Weatherall Institute of Molecular Medicine, has found that dominant T cell responses years after infection are associated with mild COVID-19 disease, and likely play important protective roles to following viral infections.

New research reveals optimal time intervals for COVID-19 vaccine boosters

Two new papers from University of Oxford scientists have shown how the immune system reacts differently depending on the length of interval between vaccine doses.

Hashem Koohy receives Wellcome Discovery Award to decode T cell immunity

Hashem Koohy, Associate Professor of Systems Immunology, has been awarded funding from Wellcome to develop computational strategies to decipher the underlying rules of adaptive T cell immunity.

AI-generated image of a glowing heart surrounded by medical alerts.

Body-in-a-chip approach reveals how immune cells respond to heart injury

Oxford scientists build a connected, ‘multi-organoid’ platform that recreates immune recruitment to the heart, opening new avenues to probe disease and test therapies.

Image of performer in the Dangerous Matter opera

How should we tell the stories of science? Upcoming Thanks for the Memories panel event at the History of Science Museum

Illustration showing immunotherapy targeting a cancer cell

New ‘off-the-shelf’ immunotherapy shows promise for treating high-risk childhood leukaemia

Scientists at the University of Oxford, together with colleagues at Imperial College London and the University of Glasgow, have developed a new type of immunotherapy that could improve outcomes for infants and children with high-risk leukaemia.

New studies reveal optimal time intervals for COVID-19 vaccine boosters

Two new papers from scientists in the Nuffield Department of Medicine and other University of Oxford institutions have shown how the immune system reacts differently depending on the length of interval between vaccine doses.

Scientists create first atlas showing cell interaction in lung fibrosis

In a collaborative new study, researchers have developed the first mathematically supported cellular map of lung tissue in idiopathic pulmonary fibrosis and uncovered key immune cell interactions that could explain why lungs fail to repair in this deadly disease with no known cure.

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