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Malignant pleural effusion (MPE) is a common condition which often causes significant symptoms to patients and costs to healthcare systems. Over the past decade, the management of MPE has progressed enormously with large scale, randomised trials answering key questions regarding optimal diagnostic strategies and effective management strategies. Despite a number of management options, including talc pleurodesis, indwelling pleural catheters and combinations of the two, treatment for MPE remains symptom directed and centered around drainage strategy. The future goals for providing improved care for patients lies in changing the treatment paradigm from a generic pathway to personalised care, based on probability of malignancy type and survival. This article reviews the current evidence base, new discoveries and future directions in the diagnosis and management of MPE.

Original publication

DOI

10.3389/fonc.2022.1053574

Type

Journal article

Journal

Front Oncol

Publication Date

2022

Volume

12

Keywords

indwelling pleural catheter (IPC), malignant pleural effusion (MPE), oncology, pleural, thoracoscopy (pleuroscopy)