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A total of 969 isolates of Campylobacter jejuni originating in the Preston, Lancashire postcode district over a 3-year period were characterized using multi-locus sequence typing. Recently developed statistical methods and a genetic model were used to investigate temporal, spatial, spatio-temporal and genetic variation in human C. jejuni infections. The analysis of the data showed statistically significant seasonal variation, spatial clustering, small-scale spatio-temporal clustering and spatio-temporal interaction in the overall pattern of incidence, and spatial segregation in cases classified according to their most likely species-of-origin.

Original publication

DOI

10.1017/S0950268810000488

Type

Journal article

Journal

Epidemiol Infect

Publication Date

10/2010

Volume

138

Pages

1384 - 1390

Keywords

Adolescent, Adult, Aged, Aged, 80 and over, Bacterial Typing Techniques, Campylobacter Infections, Campylobacter jejuni, Child, Child, Preschool, Cluster Analysis, DNA Fingerprinting, DNA, Bacterial, England, Enteritis, Female, Foodborne Diseases, Genotype, Humans, Infant, Infant, Newborn, Male, Middle Aged, Molecular Epidemiology, Seasons, Sequence Analysis, DNA, Time Factors, Young Adult