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Shigella pathogenesis has confounded researchers for years because of its narrow host selectivity and extraordinary infectious capability. In this issue of Immunity, Xu et al. (2018) identify a cunning mechanism whereby Shigella hijacks human α-defensin 5 to enhance its adhesion and subsequent invasion.

Original publication

DOI

10.1016/j.immuni.2018.05.015

Type

Journal article

Journal

Immunity

Publication Date

19/06/2018

Volume

48

Pages

1070 - 1072

Keywords

Bacterial Adhesion, Dysentery, Bacillary, Humans, Shigella, alpha-Defensins