Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

· The strong HLA associations of many inflammatory arthropathies imply an underlying autoimmune pathology. · The function of HLA molecules in the recognition of viral and bacterial antigens is now well described and has important implications for the pathogenesis of diseases such as ankylosing spondylitis, reactive arthritis and rheumatoid arthritis. · HLA-B27 is strongly associated with ankylosing spondylitis and has played an important role in defining a group of related spondyloarthropathies. · HLA genes contribute less than half of the genetic basis of these diseases. · Whole genome screening is a power tool to detect other genes relevant to these conditions.

Original publication

DOI

10.1259/img.11.2.110073

Type

Journal article

Journal

Imaging

Publication Date

01/01/1999

Volume

11

Pages

73 - 77