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Innate lymphoid cells (ILCs) are a family of developmentally related cells that are involved in immunity and in tissue development and remodelling. Recent research has identified several distinct members of this family. Confusingly, many different names have been used to characterize these newly identified ILC subsets. Here, we propose that ILCs should be categorized into three groups based on the cytokines that they can produce and the transcription factors that regulate their development and function.

Original publication

DOI

10.1038/nri3365

Type

Journal article

Journal

Nat Rev Immunol

Publication Date

02/2013

Volume

13

Pages

145 - 149

Keywords

Animals, Biomarkers, Guidelines as Topic, Humans, Immunity, Innate, Immunophenotyping, Lymphocytes