Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Siegelman and colleagues demonstrate unexpected synergism of CD44 and VLA-4 during lymphocyte extravasation. This is the first time that molecules mediating rolling and firm adhesion have been shown to associate biochemically leading to direct functional cooperation.

Type

Journal article

Journal

Immunity

Publication Date

04/2004

Volume

20

Pages

361 - 362

Keywords

Animals, Cell Adhesion, Humans, Hyaluronan Receptors, Inflammation, Integrin alpha4beta1, Leukocyte Rolling, T-Lymphocytes