New trial using skin patches as an ‘early warning system’ to spot lung transplant rejection
17 April 2024
A new trial, SENTINEL, is set to investigate if skin patches can be used as an early warning system to identify if lung transplants are being rejected, so treatment can begin sooner, reducing the chance of longer lasting organ damage.
Serum Institute of India and University of Oxford strike landmark licensing agreement for Meningitis-B vaccine
16 April 2024
Serum Institute of India Pvt. Ltd (SIIPL), in collaboration with the University of Oxford, is developing a novel solution for Men-B disease, advancing global accessibility to life-saving vaccines.
Aerosol human infection model gives hope for TB vaccine development
16 April 2024
University of Oxford researchers have for the first time established a controlled human infection model for tuberculosis (TB) that infects people via the lungs – the way TB enters the body.
New study reveals how T cells gain and maintain tolerance to gut bacteria
3 April 2024
The immune system in the intestine maintains a careful balance, tolerating our long-term resident (commensal) gut bacteria while defending against invading pathogens. Under certain circumstances, dysregulation of our intestinal immune response to commensal and pathogenic microbes can drive inflammatory disease.
Novel pairing of proteins controls tumour growth
3 April 2024
New research by the CAMS Oxford Institute, the MRC Translational Immune Discovery Unit and the Kennedy Institute researchers describes a novel pairing of integrins which could improve T cell control of cancer.
Thanks for the Memories Immunology Workshop at the Science and Industry Museum, Manchester
28 March 2024
The Thanks for the Memories public engagement programme – bringing together the worlds of immunology research and music composition for secondary school students in Manchester and Oxford – had a fantastic day with Manchester Co-op Academy students at the Science and Industry Museum in Manchester on Friday 8th March.
Developing the world's first lung cancer vaccine
26 March 2024
Researchers at the Nuffield Department of Medicine, the Francis Crick Institute and University College London have been granted £1.7 million of funding from Cancer Research UK and the CRIS Cancer Foundation to develop a lung cancer vaccine. The group includes Professor Tim Elliott, Kidani Professor of Immuno-oncology at NDM.
PD-1 gets an “A” for team-work
8 March 2024
A new understanding of the PD-1 axis (programmed death cell) could help shape ongoing efforts to improve treatments for cancer and autoimmune diseases.
Ricardo Fernandes awarded a Cancer Research UK Immunology Project Award
8 March 2024
CAMS-Oxford Institute Principal Investigator, Ricardo Fernandes, has been awarded a competitive grant from Cancer Research UK to study anti-tumour T cell responses.
New study suggests antiviral treatment course is not long enough to treat COVID-19 in at risk patients
26 February 2024
New research published in Nature Communications suggests that the currently recommended five-day course of molnupiravir, an antiviral treatment, may not be long enough to treat COVID-19.
Study finds high number of persistent COVID-19 infections in the general population
22 February 2024
A new study led by the Big Data Institute at NDM has found persistent COVID-19 infections are surprisingly common, with around one to three in every 100 infections lasting a month or longer.
Rising antimicrobial resistance in enteric fever across 75 countries
16 February 2024
Recent findings by the Global Research on Antimicrobial Resistance Project at NDM's Centre for Tropical Medicine and Global Health revealed the resistance patterns for a priority pathogen--also known as typhoid fever--with high mortality and morbidity in resource-constrained settings.
R21 malaria vaccine phase III trial confirms high efficacy and safety
5 February 2024
The phase III trial data results of the R21/Matrix-M vaccine, developed by the Jenner Institute and the Serum Institute of India have confirmed high efficacy and supported regulatory approvals and licensure in several African countries.
World Cancer Day 2024: Highlighting cancer research at the MRC WIMM
4 February 2024
This World Cancer Day, we heard from four Group Leaders at the MRC Weatherall Institute of Molecular Medicine about their work and how their groups are helping in the fight against cancer.
AI-based method provides insights for predicting colorectal cancer outcomes
2 February 2024
The largest multiparameter immunoprofiling study in cancer to date has suggested an underappreciated role of a subset of immune cells in determining the risk of bowel cancer relapse after surgery.
Study uncovers how the Hepatitis B virus adapts
30 January 2024
A new hepatitis B study reveals how viruses adapt to low-oxygen environments, such as those found deep within the liver, opening up possible new therapeutic targets for liver pathogens. NDM researchers have identified hypoxia-inducible factors (HIFs) playing an important role in the regulation of editing of viral RNAs in low oxygen conditions.
UK minister meets with Oxford pandemic researchers
29 January 2024
Researchers at the Jenner Institute, the Oxford Vaccine Group and the Pandemic Sciences Institute hosted the Rt Hon Andrew Mitchell MP, Minister for Development and Africa, to the laboratories and clinics of several of its vaccine development groups.
Research into ancient DNA sheds new light on cause of Multiple Sclerosis and other neurodegenerative diseases
11 January 2024
Research led by scientists at the Universities of Oxford, Cambridge, Copenhagen, Bristol and California (Berkeley) reveals the evolutionary origins of multiple sclerosis (MS). This new insight into the genetic architecture of this disease changes scientists’ view of its causes and has implications for its treatment, as well as paving the way for further investigations into other diseases.