Professor Gil McVean
Contact information
Research groups
Colleges
Gil McVean
FRS FMedSci
Director, Big Data Institute; Professor of Statistical Genetics, Nuffield Department of Medicine
- Head of Bioinformatics and Statistical Genetics
- University Lecturer in Mathematical Genetics
- Group Head / PI and Unit Director,
My research covers several areas in the analysis of genetic variation, combining the development of methods for analysing high throughput sequencing data, theoretical work and empirical analysis. Of particular interest are: the analysis of recombination from population genetic data, dissecting signals of disease association within the HLA, methods for inferring genealogical history from DNA sequence data and de novo sequence assemblyfor the discovery of genetic variation. I am a member of the Mathematical Genetics Group in the Department of Statistics and Acting Director of the new Oxford Big Data Institute.
Recent publications
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The origins and relatedness structure of mixed infections vary with local prevalence of P. falciparum malaria
Journal article
MCVEAN G. et al, (2019), eLife
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Detection of simple and complex de novo mutations without, with, or with multiple reference sequences
Journal article
Garimella K. et al, (2019)
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A genetics-led approach defines the drug target landscape of 30 immune-related traits
Journal article
Fang H. et al, (2019), Nature Genetics
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Predictable patterns of CTL escape and reversion across host populations
and viral subtypes in HIV-1 evolution
Journal article
Palmer DS. et al, (2019), arxiv
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Coupling Wright-Fisher and coalescent dynamics for realistic simulation of population-scale datasets
Journal article
Nelson D. et al, (2019)