Professor Gil McVean
Director, Big Data Institute; Professor of Statistical Genetics, Nuffield Department of Medicine
- Head of Bioinformatics and Statistical Genetics
- University Lecturer in Mathematical Genetics
- Group Head / PI and Unit Director,
My research covers several areas in the analysis of genetic variation, combining the development of methods for analysing high throughput sequencing data, theoretical work and empirical analysis. Of particular interest are: the analysis of recombination from population genetic data, dissecting signals of disease association within the HLA, methods for inferring genealogical history from DNA sequence data and de novo sequence assemblyfor the discovery of genetic variation. I am a member of the Mathematical Genetics Group in the Department of Statistics and Acting Director of the new Oxford Big Data Institute.
Elucidating relationships between P.falciparum prevalence and measures of genetic diversity with a combined genetic-epidemiological model of malaria.
Hendry JA. et al, (2021), PLoS Comput Biol, 17
The impact of age on genetic risk for common diseases.
Jiang X. et al, (2021), PLoS Genet, 17
Accounting for long-range correlations in genome-wide simulations of large cohorts.
Nelson D. et al, (2020), PLoS genetics, 16
Identifying cross-disease components of genetic risk across hospital data in the UK Biobank.
Cortes A. et al, (2020), Nat Genet, 52, 126 - 134
Insights into malaria susceptibility using genome - wide data on 17,000 individuals from Africa, Asia and Oceania
BAND G. et al, (2019), Nature Communications