Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

COVID-19 Literature Reviews

A group of post-docs and DPhil students in the Medical Sciences Division are voluntarily reviewing some of the immunology-focussed COVID-19 literature, particularly pre-prints. This initiative has been organised by the Kennedy Institute for Rheumatology Journal Club. Disclaimer: all views are our own!

pile of papers

Intestinal inflammation modulates the expression of ACE2 and TMPRSS2 and potentially overlaps with the pathogenesis of SARS-CoV-2 related disease

Date:

GI bioinformatics immunology/immunity

Single-cell longitudinal analysis of SARS-CoV-2 infection in human bronchial epithelial cells

Date:

bioinformatics

SARS-CoV-2 activates lung epithelia cell proinflammatory signaling and leads to immune dysregulation in COVID-19 patients by single-cell sequencing

Date:

bioinformatics immunology/immunity inflammation

Cytokine profile in plasma of severe COVID-19 does not differ from ARDS and sepsis

Date:

clinical immunology/immunity inflammation

The SARS-CoV-2 spike protein primes inflammasome-mediated interleukin-1- beta secretion in COVID-19 patient-derived macrophages

Date:

biochemistry cell biology immunology/immunity inflammation molecular biology

Tropism, replication competence, and innate responses of the coronavirus SARS-CoV-2 in human respiratory tract and conjunctiva: an analysis in ex-vivo and in-vitro cultures

Date:

immunology/immunity virology

Symptomatic SARS-CoV-2 infections display specific IgG Fc structures

Date:

clinical immunology/immunity

A high-throughput neutralizing antibody assay for COVID-19 diagnosis and vaccine evaluation

Date:

clinical diagnostics

The SARS-CoV-2 cytopathic effect is blocked with autophagy modulators

Date:

autophagy/lysosome drug discovery/repurposing therapeutics

Convergent Antibody Responses to SARS-CoV-2 Infection in Convalescent Individuals

Date:

clinical immunology/immunity

The SARS-CoV-2 T-cell immunity is directed against the spike, membrane, and nucleocapsid protein and associated with COVID 19 severity

Date:

immunology/immunity

Longitudinal high-throughput TCR repertoire profiling reveals the dynamics of T cell memory formation after mild COVID-19 infection

Date:

immunology/immunity

Thymosin alpha 1 (Tα1) reduces the mortality of severe COVID-19 by restoration of lymphocytopenia and reversion of exhausted T cells

Date:

clinical drug discovery/repurposing immunology/immunity

SARS-CoV-2 infection protects against rechallenge in rhesus macaques

Date:

immunology/immunity vaccines virology

Broad-spectrum virucidal activity of bacterial secreted lipases against flaviviruses, SARS-CoV-2 and other enveloped viruses

Date:

proteomics therapeutics virology

Immunologic perturbations in severe COVID-19/SARS-CoV-2 infection

Date:

clinical immunology/immunity

Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2

Date:

biochemistry immunology/immunity molecular biology structural biology

DNA vaccine protection against SARS-CoV-2 in rhesus macaques

Date:

immunology/immunity vaccines virology

Type I and Type III IFN Restrict SARS-CoV-2 Infection of Human Airway Epithelial Cultures

Date:

cell biology immunology/immunity inflammation virology

SARS-CoV-2 targets cortical neurons of 3D human brain organoids and shows neurodegeneration-like effects

Date:

cell biology neurobiology

Load More

Additional resources

Oxford COVID-19 Evidence Service (Oxford CeBM)

COVID Preprints

Nature - Pick of the coronavirus papers (Nature)

Cell Press Coronavirus Resource Hub (Cell Press)

Who's who

HUGE THANKS TO THE FOLLOWING OXFORD STUDENTS AND POST-DOCS WHO HAVE BEEN REVIEWING THESE ARTICLES;

Enas Abushah, David Ahern, Jennifer Alderson, Hannah Almuttaqi, Dominic Alonzi, Ghada Alsaleh, Tharini Askumar, Vicky Batchelor, Dorothee Berthold, Tehmina Bharucha, Henry Blest, Helene Borrmann, Mariana Borsa, Rowie Borst, Juliane Brun, Athena Cavounidis, Pablo Cespedes, Anne Chauveau, Lise Chauveau, Liliana Cifuentes Gutierrez, Jennifer Cole, Isabella Collins, Laura Collins, Ewoud Compeer, Clarissa Coveney, Amy Cross, Sara Danielli, Linnea Drexhage, Fabian Fischer, Anis Gammage, Lee Garner, Valentina Gifford, Maria Gomez Vazquez, Cornelia Heuberger, Alina Janney, Kathrin Jansen, Rebecca Jeffery, Elizabeth Jennings, Stuart Keppie, Fangfang Lu, Iona Manley, Elizabeth Mann, Anna Marzeda, Julie Mazet, Linda Mies, Hayat Muhammad, Zahra Oubihi, Sumeet Pandey, Clara Pavillet, Claire Pearson, Garbiela Pirgova, Max Quastel, Niamh Richmond, Felix Richter, Rachel Rigby, Alice Robinson, Arvind Sami, Raphael Sanches Peres, Barbora Schonfeldova, Cariad Shorten,Michael Tellier, Emily Thornton, Lion Uhl, Erinke Van Grinsven, Lihui Wang, Joseph Wilson, Isaac Wong, Shamsideen Yusuf, Kristina Zec, Dingxi Zhou, Amanda Zhu

AND TO THE FOLLOWING UNIVERSITY OF OXFORD PIS WHO EDIT THE REVIEWS;

Carolina Arancibia, Tal Arnon, Jelena Bezbradica Mirkovic, Mark Coles, Calliope Dendrou, Lynn Dustin, Fadi Issa, Jethro Johnson, Luke Jostins, Petros Ligoxygakis, Anita Milicic, Jan Rehwinkel, Quentin Sattentau, Katja Simon, Angus Wann, Richard Williams

COVID-19 publications from within the Medical Sciences Division

 

Find out more