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COVID-19 Literature Reviews

A group of post-docs and DPhil students in the Medical Sciences Division are voluntarily reviewing some of the immunology-focussed COVID-19 literature, particularly pre-prints. This initiative has been organised by the Kennedy Institute for Rheumatology Journal Club. Disclaimer: all views are our own!

pile of papers

Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes

Date:

clinical diagnostics molecular biology structural biology

In vivo antiviral host response to SARS-CoV-2 by viral load, sex, and age

Date:

bioinformatics clinical immunology/immunity inflammation

Proteomic blood profiling in mild, severe and critical COVID-19 patients

Date:

clinical proteomics

A Potently Neutralizing Antibody Protects Mice against SARS-CoV-2 Infection

Date:

immunology/immunity

Elevated Nucleoprotein-Induced Interferon-γ Release in COVID-19 Patients Detected in a SARS-CoV-2 Enzyme-Linked Immunosorbent Spot Assay

Date:

diagnostics immunology/immunity

Neuroinvasive potential of SARS-CoV-2 revealed in a human brain organoid model

Date:

cell biology inflammation molecular biology virology

Intrafamilial Exposure to SARS-CoV-2 Induces Cellular Immune Response without Seroconversion

Date:

clinical diagnostics immunology/immunity

Tocilizumab and steroid treatment in patients with COVID-19 pneumonia

Date:

clinical drug discovery/repurposing therapeutics

In silico immune infiltration profiling reveals the role of naïve B cells in lung tissues of COVID-19 patients

Date:

bioinformatics clinical immunology/immunity

Spectrum of innate and adaptive immune response to SARS CoV 2 infection across asymptomatic, mild and severe cases; a longitudinal cohort study

Date:

clinical immunology/immunity inflammation

Neuropilin-1 facilitates SARS-CoV-2 cell entry and provides a possible pathway into the central nervous system

Date:

bioinformatics cell biology clinical molecular biology virology

Two distinct immunopathological profiles in lungs of lethal COVID-19

Date:

bioinformatics clinical imaging immunology/immunity inflammation

SARS-CoV-2 infection and replication in human fetal and pediatric gastric organoids

Date:

GI bioinformatics cell biology

Longitudinal immunological analyses reveal inflammatory misfiring in severe COVID-19 patients

Date:

bioinformatics clinical immunology/immunity inflammation therapeutics

Hypoferremia predicts hospitalization and oxygen demand in COVID-19 patients

Date:

clinical diagnostics inflammation

Antiviral Drug Screen of Kinase inhibitors Identifies Cellular Signaling Pathways Critical for SARS-CoV-2 Replication

Date:

drug discovery/repurposing virology

Deregulated cellular circuits driving immunoglobulins and complement consumption associate with the severity of COVID-19

Date:

cell biology clinical immunology/immunity inflammation

Early temporal dynamics of cellular responses to SARS-CoV-2

Date:

bioinformatics cell biology immunology/immunity virology

Genome-wide CRISPR screen reveals host genes that regulate SARS-CoV-2 infection

Date:

bioinformatics cell biology drug discovery/repurposing molecular biology virology

NK cell receptor NKG2C deletion and HLA-E variants are risk factors for severe COVID-19

Date:

clinical immunology/immunity

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Additional resources

Oxford COVID-19 Evidence Service (Oxford CeBM)

COVID Preprints

Nature - Pick of the coronavirus papers (Nature)

Cell Press Coronavirus Resource Hub (Cell Press)

Who's who

HUGE THANKS TO THE FOLLOWING OXFORD STUDENTS AND POST-DOCS WHO HAVE BEEN REVIEWING THESE ARTICLES;

Enas Abushah, David Ahern, Jennifer Alderson, Hannah Almuttaqi, Dominic Alonzi, Ghada Alsaleh, Tharini Askumar, Vicky Batchelor, Dorothee Berthold, Tehmina Bharucha, Henry Blest, Helene Borrmann, Mariana Borsa, Rowie Borst, Juliane Brun, Athena Cavounidis, Pablo Cespedes, Anne Chauveau, Lise Chauveau, Liliana Cifuentes Gutierrez, Jennifer Cole, Isabella Collins, Laura Collins, Ewoud Compeer, Clarissa Coveney, Amy Cross, Sara Danielli, Linnea Drexhage, Fabian Fischer, Anis Gammage, Lee Garner, Valentina Gifford, Maria Gomez Vazquez, Cornelia Heuberger, Alina Janney, Kathrin Jansen, Rebecca Jeffery, Elizabeth Jennings, Stuart Keppie, Fangfang Lu, Iona Manley, Elizabeth Mann, Anna Marzeda, Julie Mazet, Linda Mies, Hayat Muhammad, Zahra Oubihi, Sumeet Pandey, Clara Pavillet, Claire Pearson, Garbiela Pirgova, Max Quastel, Niamh Richmond, Felix Richter, Rachel Rigby, Alice Robinson, Arvind Sami, Raphael Sanches Peres, Barbora Schonfeldova, Cariad Shorten,Michael Tellier, Emily Thornton, Lion Uhl, Erinke Van Grinsven, Lihui Wang, Joseph Wilson, Isaac Wong, Shamsideen Yusuf, Kristina Zec, Dingxi Zhou, Amanda Zhu

AND TO THE FOLLOWING UNIVERSITY OF OXFORD PIS WHO EDIT THE REVIEWS;

Carolina Arancibia, Tal Arnon, Jelena Bezbradica Mirkovic, Mark Coles, Calliope Dendrou, Lynn Dustin, Fadi Issa, Jethro Johnson, Luke Jostins, Petros Ligoxygakis, Anita Milicic, Jan Rehwinkel, Quentin Sattentau, Katja Simon, Angus Wann, Richard Williams

COVID-19 publications from within the Medical Sciences Division

 

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