Vaccines is an international, peer-reviewed, open access journal published monthly online by MDPI.
Nicholas is a Postdoctoral Fellow of the Laboratory of Professor Paul Klenerman at Translational Gastroenterology Unit, University of Oxford. His primary research interest is in understanding the fundamental immune processes that regulate the immunogenicity and efficacy of vaccines. His current project is focused on understanding the function and development of a population of T cells that are abundant in human mucosal tissues and display traits characteristic of conventional T cells as well as traits of innate immune cells, such as NK cells. This cell population is defined by the expression of the molecule CD161, and these cells can make up more than 50% of the CD8+ T cells found within portions of the intestinal tract.