Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Search results

Found 6 matches for

Kennedy researchers and Columbia University engineers discover geometric underpinnings of T-cell stimulation through precise engineering of T-cell receptor geometry, building a 3D nanofabricated biomimetic surface that simulates the key components of an antigen-presenting cell.

Composite of a scanning electron micrograph and immunofluorescence image showing a T cell (SEM) on an array of clusters of T cell receptor ligands, fluorescently labeled red. The green fluorescent signal comes from phosphorylation of a component of the T cell receptor, indicating that triggering has occurred (i.e., the T cell has been stimulated).
Composite of a scanning electron micrograph and immunofluorescence image showing a T cell (SEM) on an array of clusters of T cell receptor ligands, fluorescently labeled red. The green fluorescent signal comes from phosphorylation of a component of the T cell receptor, indicating that triggering has occurred (i.e., the T cell has been stimulated).

New therapeutic target identified in spondyloarthritis

Kennedy

A new study published in Nature Communications identifies a key driver of joint and intestinal inflammation that could lead to future treatment of the chronic inflammatory disease.

Researchers identify link in the treatment of inflammatory bowel disease (IBD)

Kennedy

A new study published in the Journal of Experimental Medicine reveals how IL-10 and PGE2 work together to prevent inflammatory tissue damage and maintain a healthy gut balance

Dissecting TNF signalling in inflammatory disease

Kennedy

New research from Dr Richard Williams’ group at the Kennedy Institute suggests a route for the development of more selective – and effective – therapies for immune-mediated inflammatory disease.

Naturally occurring compound spermidine boosts vaccine responses in old mice

Kennedy

A new study by Kennedy Institute's Professor Katja Simon, and colleagues published in Molecular Cell shows that spermidine, a naturally occurring metabolite found in most human cell types, boosts antibody production in both old mice and immune cells from the elderly.

Dialling down inflammation in psoriasis

Kennedy

A collaborative study between the Kennedy Institute and MRC Weatherall Institute of Molecular Medicine (MRC WIMM) identifies a new pathway that limits the severity of inflammatory skin disease.

Geometry is key to T-cell triggering

Kennedy

Kennedy researchers and Columbia University engineers discover geometric underpinnings of T-cell stimulation through precise engineering of T-cell receptor geometry, building a 3D nanofabricated biomimetic surface that simulates the key components of an antigen-presenting cell.

Similar stories

New therapeutic target identified in spondyloarthritis

Kennedy

A new study published in Nature Communications identifies a key driver of joint and intestinal inflammation that could lead to future treatment of the chronic inflammatory disease.

Researchers identify link in the treatment of inflammatory bowel disease (IBD)

Kennedy

A new study published in the Journal of Experimental Medicine reveals how IL-10 and PGE2 work together to prevent inflammatory tissue damage and maintain a healthy gut balance

Dissecting TNF signalling in inflammatory disease

Kennedy

New research from Dr Richard Williams’ group at the Kennedy Institute suggests a route for the development of more selective – and effective – therapies for immune-mediated inflammatory disease.

Naturally occurring compound spermidine boosts vaccine responses in old mice

Kennedy

A new study by Kennedy Institute's Professor Katja Simon, and colleagues published in Molecular Cell shows that spermidine, a naturally occurring metabolite found in most human cell types, boosts antibody production in both old mice and immune cells from the elderly.

Dialling down inflammation in psoriasis

Kennedy

A collaborative study between the Kennedy Institute and MRC Weatherall Institute of Molecular Medicine (MRC WIMM) identifies a new pathway that limits the severity of inflammatory skin disease.