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Leducq-funded transatlantic network set to pioneer new diagnosis and treatment of heart disease

DPAG

Professor David Paterson, in collaboration with the UCLA’s Professor Kalyanam Shivkumar, has been awarded a prestigious Leducq International Network of Excellence Program Award of $8 million (£6.3M) to set up a major new transatlantic network linking world leading researchers from the USA and Europe to develop ‘Bioelectronics for neurocardiology diagnosis and therapeutics’.

Researchers describe how cancer cells can defend themselves from the consequences of certain genetic defects

DPAG

Researchers in Department of Physiology, Anatomy and Genetics have identified a rescue mechanism that allows cancers to overcome the consequences of inactivating mutations in critically important genes.

New target identified for repairing the heart after heart attack

DPAG

An immune cell is shown for the first time to be involved in creating the scar that repairs the heart after damage. The Riley Group study was funded by the British Heart Foundation and led by BHF CRE Intermediate Transition Research Fellow Dr Filipa Simões.

Malnutrition linked with increased risk of Zika birth defects

DPAG

The severity of Zika virus-related deformations in babies has been shown to be affected by environmental factors such as maternal nutrition. The study was partially funded by a joint MRC Grant between DPAG's Professor Zoltán Molnár and Associate Professor Patricia Garcez of the Federal University of Rio de Janeiro.

Leptin is the missing piece in the immunometabolism puzzle

DPAG

Associate Professor Ana Domingos reviews the identification of the hormone leptin and explores its significance in the function of immune cells in obesity.