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Inflammatory bowel disease and Crohn's disease in particular, is a common cause of intestinal failure. Current therapeutic options include home parenteral nutrition and intestinal transplantation. For most patients, home intravenous therapy including parenteral nutrition, with a good probability of long-term survival, is the favoured choice. However, in selected patients, with specific features that may shorten survival or complicate home parenteral nutrition, intestinal transplantation presents a viable alternative. We present survival, complications, quality of life and economic considerations that currently influence individualised decision-making between home parenteral nutrition and intestinal transplantation.

Original publication




Journal article


World J Gastroenterol

Publication Date





3153 - 3163


Complications, Crohn’s disease, Home parenteral nutrition, Inflammatory bowel disease, Intestinal failure, Intestinal transplantation, Quality of life, Survival, Catheterization, Crohn Disease, Humans, Inflammatory Bowel Diseases, Intestine, Small, Liver Diseases, Parenteral Nutrition, Home, Postoperative Complications, Quality of Life, Recurrence, Sepsis, Treatment Outcome