Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Cytotoxic T-lymphocyte (CTL) and T-helper-cell responses in various mouse strains were monitored. Protective CTL responsiveness against three proteins of vesicular stomatitis virus was H-2 linked and inducible only in half of the 15 combinations tested (each of five H-2 haplotypes combined with each of three viral proteins), whereas biologically relevant T-helper-cell responses were inducible in all. This suggests that vesicular stomatitis virus exhibits more T-helper-cell than CTL epitopes.

Type

Journal article

Journal

J Virol

Publication Date

06/1993

Volume

67

Pages

3680 - 3683

Keywords

Animals, Antibodies, Viral, Antigens, Viral, B-Lymphocytes, CD4 Antigens, CD8 Antigens, Capsid, Epitopes, H-2 Antigens, Membrane Glycoproteins, Mice, Mice, Inbred Strains, T-Lymphocyte Subsets, T-Lymphocytes, T-Lymphocytes, Cytotoxic, T-Lymphocytes, Helper-Inducer, Vesicular stomatitis Indiana virus, Viral Core Proteins, Viral Envelope Proteins, Virus Diseases