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Gene transfer to the corneal endothelium has potential for modulating rejection of corneal grafts. It can also serve as a convenient and useful model for gene therapy of other organs. In this article we review the work carried out in our laboratory using both viral and nonviral vectors to obtain gene expression in the cornea.

Original publication

DOI

10.1164/ajrccm.162.supplement_3.15tac11

Type

Journal article

Journal

Am J Respir Crit Care Med

Publication Date

10/2000

Volume

162

Pages

S194 - S200

Keywords

Adenoviridae, Animals, Endothelium, Corneal, Gene Transfer Techniques, Genetic Vectors, Graft Rejection, Humans, Transplantation Tolerance