Acute HIV-1 Infection.
Cohen MS., Shaw GM., McMichael AJ., Haynes BF.
In 2009, the United Nations Estimated that 33.2 Million People worldwide were living with human immunodeficiency virus type 1 (HIV-1) infection and that 2.6 million people had been newly infected. The need for effective HIV-1 prevention has never been greater. In this review, we address recent critical advances in our understanding of HIV-1 transmission and acute HIV-1 infection. Fourth-generation HIV-1 testing, now available worldwide,, will allow the diagnosis of infection in many patients and may lead to new treatments and opportunities for prevention.