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News

Sooraj Achar wins the 2025 Peter Medawar Prize for Immunology

The 2025 prize was awarded to Sooraj Achar (NCI/Kennedy Institute) for his outstanding contribution to understanding T cell antigen recognition, particularly in the context of cancer immunotherapy, and wider contributions to the immunology community.

Susanna Dunachie and Caesar Atuire appointed co-Associate Directors of Oxford Global Health

New episode of To Immunity and Beyond: Analysis of the diverse antigenic landscape of the malaria protein RH5 identifies a potent vaccine-induced human public antibody clonotype

Dr Kirsty McHugh and Dr Carolyn Nielsen discuss a recent Cell article: ‘Analysis of the diverse antigenic landscape of the malaria protein RH5 identifies a potent vaccine-induced human public antibody clonotype’.

Two female at the trial

Oxford launches first human trial of aerosol vaccine delivery

The University of Oxford in partnership with the Coler Lab at Seattle Children’s Research Institute (SCRI) has begun a new clinical trial called TB045, which aims to test tuberculosis (TB) vaccine safety and the host immune response in a first-in-human aerosol mycobacterial challenge infection model with healthy adult volunteers.

Photograph of a person being vaccinated

Lower-dose yellow fever vaccine as effective as the current standard

In a recent study, researchers at the KEMRI Wellcome Trust Research Programme in Kenya have discovered that a low-dose of the yellow fever vaccine is as effective as the current standard dose.

Immune response may be harnessed to control HIV

Researchers have unveiled primary trial results that show encouraging advances in HIV treatment driven by immune-based therapies. New antibody therapies could offer alternative to current treatments.

To Immunity and Beyond Podcasts logo (graphic of immune cells)

New episode of To Immunity and Beyond: Starvation and infection: The role of sickness-associated anorexia in metabolic adaptation during acute infection

Doctor looking for tuberculosis in lung scan

Researchers receive funding to develop new therapies for drug-resistant tuberculosis

The Ineos Oxford Institute for antimicrobial research (IOI) has awarded £5 million to a group of interdisciplinary researchers from NDM and other departments at the University, to develop new therapies for drug-resistant tuberculosis.

Health care workers in Bangladesh

Bangladesh malaria vaccine and drug administration trial begins

After more than a year of community engagement and preparation in 100 villages with over 12,000 inhabitants across the Chittagong Hill Tracts, a mass malaria vaccine (R21/Matrix M) and drug administration (DHA, piperaquine, and single low dose primaquine) study was launched on 15 February.

The pancreas

Pancreatic cancer immune map provides clues for precision treatment targeting

Study shows why there are differences in prognosis between different pancreatic tumours and identifies potential avenues for improved treatment approaches.

Oxford and GSK launch £50m programme to advance cancer research

Global biopharma company GSK invests up to £50 million in a collaboration with Oxford to advance the understanding of how cancer develops, which could inform future development of vaccines to prevent cancer.

Oxford University buildings

BSI Oxford Immunology Symposium 2025

T cells (red) targeting a cancer cell (green)

New episode of To Immunity and Beyond: Optimising CAR-T cell sensitivity by engineering matched extracellular sizes between CAR/antigen and CD2/CD58 adhesion complexes

Blood samples

New blood test could enable early detection of multiple cancers

A new blood test – powered by machine learning – has shown real promise in detecting multiple types of cancer in their earliest stages, when the disease is hardest to detect. Developed by a team of researchers and co-lead by the Centre for Human Genetics’ Dr Dimitris Vavoulis, the test accurately detected six cancer types and could distinguish between people with and without cancer.

Reversing resistance to cancer immune therapy with antibodies

A new study led by Professor Ignacio Melero of NDM's Centre for Immuno-oncology and the University of Navarra and has highlighted a way to combat resistance to cancer immunotherapy in solid tumours by using antibodies that target GDF-15 protein.

Researchers provide a perspective on mapping the bone marrow using new spatial transcriptomic technologies

RDM researchers have outlined the potential benefits and limitations of new spatial transcriptomic technologies for mapping the bone marrow in patients with blood cancer.

Trial results for first vaccine against blood-stage malaria show it is well-tolerated and offers effective protection

Results of a clinical trial into a new malaria vaccine candidate (RH5.1/Matrix-M) show it is well-tolerated and offers effective protection against the blood-stage of the disease – the first inoculation to do so.

Woman using asthma inhaler

First new treatment for asthma attacks in 50 years

An injection given during some asthma and chronic obstructive pulmonary disease (COPD) attacks is more effective than the current treatment of steroid tablets, reducing the need for further treatment by 30 percent.

Woman sneezing into a tissue

Reconstructing a lifetime of flu infections to understand long-term trends

Using antibody data and mathematical modelling, a new study from researchers at the Pandemic Sciences Institute estimates annual patterns of influenza infection and protection over the past fifty years.

Launch of 'To Immunity and Beyond' podcast series

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