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News

Coughing woman

ORTU awarded £2.8m to study treatment for pleural infection

The Oxford Respiratory Trials Unit (ORTU) at the Nuffield Department of Medicine has been awarded a £2.8 million grant from the National Institute for Health and Care Research Health Technology Assessment (NIHR HTA) to conduct the MIST4 study.

A malaria febrile child diagnosed and treated in early morning Nov 2023 in Mtwara, Tanzania

Policy changes needed as drug-resistant malaria spreads in East Africa

The efficacy of artemisinin derivatives, the cornerstone of current treatments for malaria, is being compromised in Africa where over 1,000 children are estimated to die each day from the disease. The spread of artemisinin-resistant malaria parasites across East Africa and beyond could result in millions more deaths without immediate health policy changes, warn experts in a paper published in Science.

Community voices shaping tuberculosis research in Viet Nam

A recent publication by OUCRU researchers, published in the journal Public Health Action, highlights the importance of community engagement in TB research.

T cells (red) targeting a cancer cell (green)

New Oxford Immunology Spin-out Company working to Improve Immunotherapy: MatchBio

Oxford immunologists Professor Omer Dushek and Professor Anton van der Merwe have founded a new company called MatchBio, which aims to apply a range of approaches to make CAR T therapy more effective.

Conceptual illustration of targeted cell therapy.

Yellowstone Biosciences spinout launches to advance cutting-edge cancer therapies

Yellowstone Biosciences, a biotechnology spinout, has launched to pioneer new cancer treatments using advanced T-cell therapies based on groundbreaking research from the MRC Weatherall Institute of Molecular Medicine at the University of Oxford.

Prime Minister of Côte d’Ivoire, Robert Beugré Mambé; Minister of Health of Côte d’Ivoire, Pierre Dimba; CEO of Gavi, Dr Sania Nishtar; Kouyate Aïcha (mother); and Diomandé Aboulaye (son, 8 months).

Côte d’Ivoire makes history as first nation to deploy R21/Matrix-M™ Malaria Vaccine

Today marks the official rollout of the new R21/Matrix-M™ malaria vaccine - co-developed by the University of Oxford and Serum Institute of India, leveraging Novavax’s Matrix-M™ adjuvant technology. In a historic step in the battle to beat malaria, the first official vaccination is due to take place in Abidjan, Côte d’Ivoire, this morning and will be subsequently rolled-out in 38 districts across the country.

Oxford scientists launch first-in-human vaccine trial for deadly Marburg virus

Scientists at the University of Oxford have launched a new clinical trial to test a vaccine to protect people against deadly Marburg virus.

Discovery of a new cell type that mediates genetic risk of heart disease

A new study has used state-of-the-art single cell multiomic techniques to discover a novel population of immune cells that mediate a substantial proportion of the genetic risk of heart disease. The characteristics of these cells make them potential targets for new treatments.

Tendons connected to the knee

Uncovering the cellular secrets of healthy tendons

Research has unveiled the intricate cellular landscape of healthy human hamstring tendons, shedding new light on this vital yet often overlooked component of our musculoskeletal system.

Cross-species immune responses could lead to innovative treatments

A new study published by Oxford researchers as part of an international collaboration in the Journal of Biological Chemistry has found that an important section of our immune system, that involves the molecule MR1 and MAIT cells, is evolutionarily conserved in multiple species.

Sepsis patients could get the right treatment faster based on their genes

Sepsis patients could be treated based on their immune system’s response to infection, not their symptoms. New research uncovers how different people respond to sepsis based on their genetic makeup, which could help identify who would benefit from certain treatments and lead to the development of targeted therapies.

Students from Greyfriars School stand in front of the stage in the concert hall.

Thanks for the Memories evening of music and science

Thanks for the Memories, Wellcome-funded public engagement project led by Prof. Paul Klenerman and composer Dr Zakiya Leeming, hosted an innovative evening of music and science at the Tingewick Hall, John Radcliffe Hospital, on 5th June.

Person with psoriasis on their arm

Psoriasis probe shows high level of arthritis symptoms in patients

Early results of an international study examining the risk of arthritis for people with psoriasis have shown a high burden of joint symptoms in 712 patients – 25% of the total studied so far.

Illustration of patient and organs and doctors

RDM launches new metabolism cross-cutting research theme

On Monday 10 June, more than 50 members of RDM met to kick off the ‘Metabolism in Molecular Medicine’ cross-cutting research theme.

Research shows early life immunity increases HIV cure/remission in male infants

New research published by scientists at the University of Oxford, the University of KwaZulu-Natal and the Africa Health Research Institute in South Africa, and the Ragon Institute of Mass General, MIT and Harvard, USA, shows that male infants are more likely to achieve HIV cure/remission than females.

A 3D render of Covid Virus

Researchers find dramatic acceleration of SARS CoV2 viral clearance rates

Running continuously since Sept 2021, the PLATCOV trial at NDM's Mahidol Oxford Tropical Medicine Research Unit has randomised over 1700 patients presenting with COVID-19 infections. Work by PLATCOV’s Dr Phrutsamon Wongnak published in the Lancet Infectious Diseases has shown that rates of oropharyngeal viral clearance have accelerated dramatically since the trial started: A SARS CoV2 viral clearance half-life in untreated patients of around 16 hours In Sept 2021 had reduced to around 9 hours by Oct 2023. The results highlight the importance of pharmacometric platform trials like PLATCOV, so that we are prepared for the next pandemic.

Group photo of members of the Oxford Microbiome Network (OMiN) at its launch event on 20 May 2024 at Keble College

New network aims to bring together microbiome researchers across Oxford

The Oxford Microbiome Network (OMiN) aims to facilitate collaborations, knowledge sharing, and access to resources for microbiome researchers across Oxford. OMiN is co-led by researchers in the Kennedy Institute of Rheumatology and the Department of Biology. The network officially launched on 20th May 2024 with an event at Keble College.

Failsworth Group students performing on stage

Thanks for the Memories performance at the Royal Northern College of Music

Thanks for the Memories, Wellcome-funded public engagement project led by Prof. Paul Klenerman and composer Dr Zakiya Leeming, hosted an innovative evening of music and science at the Royal Northern College of Music in early May.

Illustration of the inside of the intestine showing individual cells.

Cancer Cell study identifies possible ways cancer treatment can lead to harmful side effects

Dr Yiqi Zhao wins the inaugural Peter Medawar Prize for Immunology

The 2024 prize was awarded to Dr Yiqi Zhao (Dunn School) for her outstanding contribution to understanding innate immunity and viral evasion, and wider contributions to the immunology community.

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