Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Accept all cookies Reject all non-essential cookies

News

How Unstable Cancer Genomes Reshape the Tumour Landscape

Chromosomal instability (CIN) is a hallmark of aggressive cancers, yet the mechanisms through which it shapes tumour behaviour and clinical outcomes remain poorly defined. With new funding from Guts UK and the University of Oxford Medical Sciences Division, Dr Bruno Beernaert, postdoctoral researcher in the Department of Oncology, is tackling this challenge by developing innovative approaches to uncover the role of CIN in tumour evolution and immune evasion.

New Oxford-led trial explores if the immune system can be trained to control HIV

Can the immune system be trained to control HIV without continuous medication? A new Oxford-led clinical trial is exploring whether immune-based strategies could support longer-term viral control after stopping antiretroviral therapy.

Podcast: Unravelling T-Cell Recognition – Insights from Immunology and AI

A conversation with Professor Hashem Koohy about possibilities for use of AI in driving forward T cell research.

Podcast: HIV in 2025 - the latest science, global burden and future outlook

A conversation with Professor Andrew McMichael, Professor Tomáš Hanke, and Dr Fon Acho about current priorities in HIV treatment and prevention.

Woman with arthritis in her hand

Kennedy scientists join world-leading researchers in ‘pivotal’ study to help arthritis patients to live drug free

The prospect of long-lasting drug-free remission for children and adults living with inflammatory arthritis is a step closer to becoming a reality, thanks to a new collaboration.

DNA glass helix

Rapamycin helps protect immune cells against DNA damage

New research carried out by Dr Loren Kell at the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS) has demonstrated for the first time that rapamycin can reduce DNA damage in immune cells, a hallmark of ageing.

Rewiring T cell co-receptors to improve the safety of cancer immunotherapy

A new study from the Dushek and van der Merwe labs demonstrates a novel strategy to reduce dangerous off-target effects in engineered T cell therapies.

What determines the fate of a T cell?

Research led by Dr Mariana Borsa at the Kennedy Institute has found that a cellular housekeeping mechanism called autophagy plays a major role in ensuring that T cells generate diverse progenies upon cell division. The findings, published in Nature Cell Biology, could help boost vaccine response in older adults.

Patients are set to benefit from new guidelines on Artificial Intelligence healthcare solutions

Kennedy researchers contribute to UK-wide AI and bioscience training initiative

Together with a group of Oxford researchers, Mark Coles, Professor of Immunology at the Kennedy Institute, will co-lead the Enabling Next-generation AI for a Bioscience-Led Economy (ENAIBLE) initiative.

A hand with blue gloves showing a blood test tube filled.

Blood test predicts risk of death in acutely ill children in lower-income countries

An international study has identified a blood-based indicator of intestinal damage and inflammation that strongly predicts mortality in sick children. The new biomarker could help to identify those children at greatest risk of dying after hospitalisation in parts of the world with limited resources.

New Study to Investigate How Immunometabolism Shapes Treatment Responses in Pancreatic Cancer

A healthier brain may reduce your risk of dementia and early death

A promotional photo of Sarah Blagden in a white lab coat. Text over the top reads 'Cancer Detectives: Finding the Cures'. Only to be used to promote agreed content around the documentary.

Professor Sarah Blagden shares cutting-edge precision prevention research at Oxford in new Channel 4 Documentary

Over the past year, Professor Blagden has been filming for Cancer Detectives: Finding the Cures, a new three-part documentary series from Channel 4 which follows three scientists on the front lines of cancer research across the UK.

Researcher pipetting a solution into a tube

Oxford and GSK launch Experimental Medicine Collaboration

GSK invests £10 million over five years to establish the Experimental Medicine Collaboration with the University of Oxford.

World’s first lung cancer prevention vaccine gets £2 million for clinical trial

People at high risk of lung cancer will soon be able to receive the first-ever experimental vaccine, 'LungVax', designed to prevent the disease, in a world-first clinical trial. The LungVax vaccine carries a series of genetic instructions which train the immune system to recognise tumour antigens on the surface of abnormal lung cells.

Neutrophil nucleus

Shaping immunity - the secrets behind the shape of neutrophils

Researchers at the Kennedy Institute have provided the most comprehensive overview to date of how the distinctive segmented nucleus of neutrophils influences their function in health and disease.

Knee pain and nerve pathways

Oxford researchers to redefine new human-based research models of pain

Professor Tonia Vincent is part of an interdisciplinary team from Oxford University leading a major new initiative which aims to redefine human-based research models for greater understanding of disease and the acceleration of new medicines.

Oxford scientists map the cells that drive Crohn’s disease fistulas

Researchers at the MRC Translational Immune Discovery Unit have identified how rare populations of abnormal cells drive the formation and persistence of fistulas - painful, tunnel-like tracts that develop in around 30% of people with Crohn’s disease - paving the way for targeted treatments.

Ignacio Melero receiving his award

Dr Ignacio Melero recognised for global contribution to advances in cancer immunotherapy

The Society for Immunotherapy of Cancer (SITC) has honoured Dr Ignacio (Nacho) Melero, Professor of Immunotherapy at NDM's Centre for Immuno-Oncology at Oxford, for his pioneering research transforming cancer treatment through immunotherapy.

Detailed map of the genome 1 pixel per nucleotide

Oxford scientists capture genome’s structure in unprecedented detail

Radcliff Department of Medicine scientists have achieved the most detailed view yet of how DNA folds and functions inside living cells, revealing the physical structures that control when and how genes are switched on.

Load More