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Monoclonal antibodies (MoAbs) have the potential to facilitate the induction of transplantation tolerance. Realization of this potential requires both a better understanding of the cellular events concerned with rejection and tolerance, and a more detailed approach to improving antibodies for therapy. This report reviews work in our laboratory directed toward these goals.

More information Original publication

DOI

10.1016/s0272-6386(88)80203-8

Type

Journal article

Publication Date

1988-02-01T00:00:00+00:00

Volume

11

Pages

154 - 158

Total pages

4

Keywords

Animals, Antibodies, Monoclonal, Graft Rejection, Humans, Immune Tolerance, Mice, Rats, T-Lymphocytes, Time Factors, Transplantation, Transplantation Immunology