Supplementary Figure 4 from Coevolution of Atypical <i>BRAF</i> and <i>KRAS</i> Mutations in Colorectal Tumorigenesis
Woolley CE., Domingo E., Fernandez-Tajes J., Pennel KAF., Roxburgh P., Edwards J., Richman SD., Maughan TS., Kerr DJ., Soriano I., Tomlinson IPM.
<p>Supplementary Figure 4. Kaplan-Meier survival curves of unadjusted overall survival (OS, months) for CRCs harboring a Class 1, 2, or 3 BRAF mutation. A: Overall survival by BRAF class irrespective of additional Ras status. B: Class 1, 2, and 3 in the absence of additional Ras. C: Class 1 and 3 absent additional Ras, and class 3 with additional Ras. Survival as shown is not corrected for covariates, whereas mixed-effects models including several covariates are reported in the main text and Table 2. Class 2 samples with survival data containing additional Ras status were insufficient for this analysis, as discussed in the main text.</p>