Microbiomes in Neverland.
Slack E., Bokulich NA.
Differentiating the effects of infant microbiota, developmental, and nutritional changes on immunological maturation during weaning is an ongoing challenge. In this issue of Cell Host & Microbe, Lubin and colleagues report a gnotobiotic mouse model that maintains neonatal-like microbiome composition into adulthood to help answer burning questions in this field.