A 3D cellular context for the macromolecular world.
Patwardhan A., Ashton A., Brandt R., Butcher S., Carzaniga R., Chiu W., Collinson L., Doux P., Duke E., Ellisman MH., Franken E., Grünewald K., Heriche J-K., Koster A., Kühlbrandt W., Lagerstedt I., Larabell C., Lawson CL., Saibil HR., Sanz-García E., Subramaniam S., Verkade P., Swedlow JR., Kleywegt GJ.
We report the outcomes of the discussion initiated at the workshop entitled A 3D Cellular Context for the Macromolecular World and propose how data from emerging three-dimensional (3D) cellular imaging techniques—such as electron tomography, 3D scanning electron microscopy and soft X-ray tomography—should be archived, curated, validated and disseminated, to enable their interpretation and reuse by the biomedical community.