Magnesium for T cells: strong to the finish!

Vardhana S., Dustin ML.

'Popeye, the Sailor' cartoons taught children that eating spinach boosts strength and helps defend against bullies. Lötscher and colleagues report that dietary deficiency of magnesium ions (Mg2+), against which eating spinach is an excellent antidote, impairs the activity of a key adhesion molecule, LFA-1, and hinders the ability of CD8+ T cells to grapple with assorted bullies, such as tumors and bacteria.

DOI

10.1016/j.it.2022.02.004

Type

Report

Publication Date

04/2022

Volume

43

Pages

277 - 279

Keywords

CD8-Positive T-Lymphocytes, Cell Adhesion Molecules, Child, Humans, Lymphocyte Function-Associated Antigen-1, Magnesium

Permalink Original publication