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Molecular analysis of Clostridium difficile (28 isolates) from children (n = 128) in Oxfordshire, United Kingdom, identified eight toxigenic genotypes. Six of these were isolated from 27% of concurrent adult C. difficile-associated infections studied (n = 83). No children carried hypervirulent PCR ribotype 027. Children could participate in the transmission of some adult disease-causing genotypes.

Original publication

DOI

10.1128/JCM.05349-11

Type

Journal article

Journal

J Clin Microbiol

Publication Date

11/2011

Volume

49

Pages

3994 - 3996

Keywords

Adolescent, Adult, Aged, Aged, 80 and over, Child, Preschool, Clostridium Infections, Clostridium difficile, DNA, Bacterial, Genotype, Humans, Infant, Middle Aged, Molecular Epidemiology, Ribotyping, United Kingdom, Young Adult