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Leucine-rich glioma-inactivated 1-antibody-encephalitis is a treatable and potentially reversible cause of cognitive and psychiatric presentations, and may mimic cognitive decline, rapidly progressive dementia and complex psychosis in older patients. This aetiology is of immediate relevance given the alternative treatment pathway required, compared with other conditions presenting with cognitive deficits.

Original publication

DOI

10.1192/bjp.2024.72

Type

Journal article

Journal

Br J Psychiatry

Publication Date

06/2024

Volume

224

Pages

252 - 257

Keywords

Dementia, leucine-rich glioma-inactivated 1, neuroimmunology, older adults, psychosis, Humans, Dementia, Autoantibodies, Encephalitis, Intracellular Signaling Peptides and Proteins, Diagnosis, Differential, Aged, Mental Health Services, Female, Male