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Mammals coexist with an extremely dense microbiota in the lower intestine. Despite the constant challenge of small numbers of microbes penetrating the intestinal surface epithelium, it is very unusual for these organisms to cause disease. In this review article, we present the different mucosal firewalls that contain and allow mutualism with the intestinal microbiota.

Original publication

DOI

10.1007/s00281-009-0174-3

Type

Journal article

Journal

Semin Immunopathol

Publication Date

07/2009

Volume

31

Pages

145 - 149

Keywords

Animals, Host-Pathogen Interactions, Humans, Intestinal Diseases, Intestinal Mucosa