Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

The prospective significance of HIV-specific cytotoxic T lymphocyte (CTL) responses in highly exposed, persistently seronegative populations is unknown. In 1996-1997 we screened for CTL responses against HIV clade B Env in 39 recently enrolled Kenyan female sex workers, and followed these women prospectively. Annual HIV incidence was 5.8%. CTL were independently associated with age and recent HIV-1 exposure,but were not prospectively associated with protection in a multivariable model that included HIV-1 exposure and duration of sex work.

Type

Journal article

Journal

AIDS

Publication Date

21/10/2004

Volume

18

Pages

2087 - 2089

Keywords

Adult, Cohort Studies, Female, Genes, env, HIV Seronegativity, HIV-1, Humans, Immunity, Cellular, Kenya, Prospective Studies, Sex Work, T-Lymphocytes, Cytotoxic