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The human lung is constantly exposed to the environment and potential pathogens. As the interface between host and environment, the respiratory epithelium has evolved sophisticated sensing mechanisms as part of its defense against pathogens. In this review, we examine how the respiratory epithelium senses and responds to influenza A virus, the biggest cause of respiratory viral deaths worldwide.

Original publication

DOI

10.1165/rcmb.2018-0247tr

Type

Journal article

Journal

American journal of respiratory cell and molecular biology

Publication Date

03/2019

Volume

60

Pages

259 - 268

Addresses

1 Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado - Anschutz Medical Campus, Aurora, Colorado.