News — Immunology

The image depicts CAR T cells killing malignant bone marrow cells that are expressing mutant CALR, illustrated as a red ‘flag’ on the cell surface.

New personalised therapy targets chronic blood cancer

2 Jul, 2026

A new form of CAR T cell therapy has been designed to find and destroy the cancer-driving cells responsible for a group of blood cancers known as myeloproliferative neoplasms (MPNs), while leaving healthy blood cells unharmed, according to a new study led by UCL and University of Oxford researchers.

Oxford researchers awarded ARIA funding to develop transformative anti-viral therapies

25 Jun, 2026

Three innovative research projects aimed at transforming how we protect against respiratory viruses, led by teams at the University of Oxford, have secured funding through the UK’s Advanced Research and Invention Agency (ARIA).

Study reveals blood stem cells can ‘remember’ inflammation

27 May, 2026

Researchers have discovered that some human blood stem cells retain a lasting “memory” of inflammation, a finding that could help explain links between ageing, chronic disease, and blood cancers

Researcher hanlding patient samples in a lab.

Reversing T cell exhaustion improves effectiveness of myeloma immunotherapies

19 May, 2026

Researchers at the Icahn School of Medicine at Mount Sinai, Bristol Myers Squibb (BMS), and the University of Oxford have discovered a way to give worn-out immune cells a second wind in the fight against multiple myeloma.

3D illustration of human immune cells - mast cell, basophil, eosinophil - involved in allergic reactions and inflammation.

New study reveals how blood cell production responds to parasite infection

11 Mar, 2026

Research led by the Nerlov Group in the MRC Molecular Haematology Unit provides the first detailed explanation of how parasite-fighting immune cells are selectively increased following infection.

Maternal and Child Health outreach site in Chediko, Mae Sot District, Tak Province. Photo Credit: Saw Poe Christ.

Oxford research highlights the global challenge of iron deficiency

9 Mar, 2026

Iron deficiency affects more than a billion people worldwide and remains a leading cause of anaemia. Oxford researchers are uncovering how iron levels shape immunity and infection - insights that could inform safer, more effective strategies to tackle iron deficiency globally.

New bone marrow model offers scalable platform for next-generation drug discovery

23 Feb, 2026

Researchers at the MRC Weatherall Institute of Molecular Medicine have developed the first combined human bone and bone marrow organoid platform capable of modelling long-term blood and immune cell production in a fully human 3D system.

Oxford scientists map the cells that drive Crohn’s disease fistulas

12 Nov, 2025

Researchers at the MRC Translational Immune Discovery Unit have identified how rare populations of abnormal cells drive the formation and persistence of fistulas - painful, tunnel-like tracts that develop in around 30% of people with Crohn’s disease - paving the way for targeted treatments.