Search results (6)
« Back to NewsNew therapeutic target identified in spondyloarthritis
20 January 2020
A new study published in Nature Communications identifies a key driver of joint and intestinal inflammation that could lead to future treatment of the chronic inflammatory disease.
Researchers identify link in the treatment of inflammatory bowel disease (IBD)
6 December 2019
A new study published in the Journal of Experimental Medicine reveals how IL-10 and PGE2 work together to prevent inflammatory tissue damage and maintain a healthy gut balance
Dissecting TNF signalling in inflammatory disease
28 October 2019
New research from Dr Richard Williams’ group at the Kennedy Institute suggests a route for the development of more selective – and effective – therapies for immune-mediated inflammatory disease.
Naturally occurring compound spermidine boosts vaccine responses in old mice
30 August 2019
A new study by Kennedy Institute's Professor Katja Simon, and colleagues published in Molecular Cell shows that spermidine, a naturally occurring metabolite found in most human cell types, boosts antibody production in both old mice and immune cells from the elderly.
Dialling down inflammation in psoriasis
9 July 2018
A collaborative study between the Kennedy Institute and MRC Weatherall Institute of Molecular Medicine (MRC WIMM) identifies a new pathway that limits the severity of inflammatory skin disease.
Geometry is key to T-cell triggering
30 April 2018
Kennedy researchers and Columbia University engineers discover geometric underpinnings of T-cell stimulation through precise engineering of T-cell receptor geometry, building a 3D nanofabricated biomimetic surface that simulates the key components of an antigen-presenting cell.