Contact information
Research groups
Alex Clarke
PhD FRCP
Principal Investigator and Honorary Consultant Rheumatologist, Nuffield Orthopaedic Centre
- Senior Clinical Research Fellow
- Honorary Consultant Rheumatologist, Nuffield Orthopaedic Centre
I qualified in Medicine from UCL in 2001, and trained in Rheumatology in London. Supported by a Wellcome Trust Clinical Research Training Fellowship, I completed a PhD on the role of autophagy in lupus in 2013, supervised by Tim Vyse at King’s College London.
After completing my medical specialist training, I moved to Oxford to join the group of Katja Simon at the Weatherall Institute of Molecular Medicine as a postdoctoral clinical fellow in 2014, again supported by the Wellcome Trust.
In 2018 I was awarded a Wellcome Trust Clinical Research Career Development Fellowship, establishing my own group here at the Kennedy Institute of Rheumatology.
Recent publications
-
The unusual metabolism of germinal center B cells.
Gracie CJ. et al, (2025), Trends Immunol
-
Asparagine availability controls germinal center B cell homeostasis.
Yazicioglu YF. et al, (2024), Sci Immunol, 9
-
Fuelling B cells: dynamic regulation of B cell metabolism
Johnstone JC. et al, (2024), Current Opinion in Immunology, 91, 102484 - 102484
-
Glycogen synthase kinase-3 is essential for Tregdevelopment and function
Kandasamy M. et al, (2024)
-
Amplification of autoimmune organ damage by NKp46-activated ILC1.
Biniaris-Georgallis S-I. et al, (2024), Nature