Research Interests

• Endometrial immune cells and their role in sub-fertility and recurrent miscarriage
• The interactions seminal fluid extracellular vesicles and endometrial cells
• Embryo factors that enhance implantation
• The influence of follicular fluids on oocyte viability
• Cytokines in pathological pregnancies, in particular IL-33 and its decoy sST2 which we have shown is highly elevated in pre-eclampsia
• Understanding the impact of pregnancy on long-term health

Research Group

Current Members

Dr Jennifer Southcombe

Miss Ali Chevassut

Mrs Lydia Brook

Ms Helena Rodriguez Caro

Former Members

Ms Erma Dewi

COLLABORATORS Professor Jan Brosens Professor Siobhan Quenby Professor Cecilia Lindgren

Biography

I graduated from the Royal Free Hospital School of Medicine, University of London in 1998. I undertook my early training in the North-West Deanery before leaving for Sydney to work. I returned to the Oxford Deanery Training Programme in 2003. During this time I undertook a MA in Medical Law and Ethics and a DPhil (with Professor Ian Sargent) in Reproductive Immunology. I was appointed as an NIHR Academic Clinical Lecturer in 2012 whilst also undertaking sub-specialty training in Reproductive Medicine. I was appointed as a Senior Clinical Fellow and Consultant Gynaecologist in 2014

The OxWATCH study

The aim of this study is to understand the impact of a first pregnancy (normal or complicated) on the long-term health of women. To do this we are recruiting women before their first successful pregnancy, following them in pregnancy and in the early post-natal period. We are currently in the pilot phase of the study. Further information on the study and how take part can be found at: http://www.osprea.ox.ac.uk/oxwatch/