Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Kerry Fisher


Associate Professor

  • Research Lecturer

Tumour microenvironment, oncolytic viruses, primary tissue and translational science

My research is focused on the tumour microenvironment, notably addressing abnormal metabolism and dysfunctional immune activity.  The structure and composition of tumour stroma can influence disease progression and, crucially, the performance of therapeutic drugs.    Conventional laboratory models do not fully recapitulate the complexity of the tumour microenvironment and our research team makes extensive use of fresh biopsy material from patients.   We have expanded this work to form a live tissue facility for the benefit of the department and our collaborators.

 For the treatment of cancer, I am exploring the use of immunotherapy approaches that are designed to capitalise on and modulate the tumour phenotype.   Oncolytic viruses are particularly interesting because they exploit both innate and adaptive immune dysfunction to replicate and spread while killing cells independently of drug resistance pathways.

 Translating new therapies to the clinic often involves working with industry, either established companies or new spin-out biotechs from the University.  Over the last 20 years I have been involved in many industrial collaborations in one form or another, helping to manage the development of new treatments from the initial innovation through to science-led clinical trials. 

Recent publications

More publications