Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Naveed Akbar

BSc (Hons), MSc, PhD, FHEA


Associate Professor of Cardiovascular Science

  • British Heart Foundation Intermediate Basic Science Research Fellow
  • Principal Investigator Radcliffe Department of Medicine
  • Research Fellow Somerville College

Extracellular Vesicles in Cardiovascular and Metabolic Diseases

Biography

I obtained my BSc (Hons) in Human Biology before completing an MSc by research in Biomedical Sciences, where I developed an interest in vascular biology and undertook interdisciplinary training to synthesize and fabricate nanoparticles for vascular targeting. I went on to obtain my PhD in Medicine and Therapeutics at the University of Dundee, where I investigated the role of innate immune signalling cascades in vascular inflammation using in vivo imaging.

As a British Heart Foundation Intermediate Basic Science Research Fellow my lab investigates the role of extracellular vesicles in cardiovascular and metabolic inflammation.

Cells within our body can transcribe, package and deliver messages to other cells, through the generation of nano-sized bubble-shaped envelopes, called extracellular vesicles (EVs). Within their enclosed spheres, these messages contain potent instructions that can alter the behaviour and biological function of its recipients, which include the very motile and sensitive cells of the immune system. I am uncovering how these shielded messages provoke the immune system into action after a heart attack. Immune system activation after a heart attack directly contributes to further injury and this in turn impacts patient health and well-being. Extracellular vesicles may provide diagnostic potential to better stratify patients for treatment following injury to the heart and as tools for therapeutic targeting.


Public Engagement 

Pint of Science (pintofscience.co.uk) aims to encourage and support the communication of the latest research in Oxford to the public in an interesting, engaging and approachable way, by bringing scientists to pubs. We attract over 800 attendees to 19 events every year. At Oxford, the festival is led and entirely run by researcher volunteers, rather than being led by a public engagement officer or organisation. I have coordinated our activities in Oxford for the past 8 years. To date Oxford Pint of Science has helped >200 researchers to particpapate in public enagement activities, enabling them to undertake further public enagement events of their own across the UK.

Recent publications

A core transcriptional signature of human trained immunity.

Journal article

Boden KA. et al, (2026), Cell Rep, 45

Adipose-Cardiac Crosstalk in Obesity-Related Atrial Fibrillation: The Emerging Role of Extracellular Vesicles.

Journal article

Akbar N. and Reilly S., (2026), JACC Basic Transl Sci, 11

Senescence-related myocardial dysfunction: keeping a young heart.

Journal article

Ajjan RA. et al, (2026), Eur Heart J

Updating MISEV: When, What, How, and Why?

Journal article

Akbar N. et al, (2026), J Extracell Vesicles, 15

Endothelial thrombomodulin-Its role in trauma-induced coagulopathy.

Journal article

Abu-Hanna J. et al, (2026), Transfusion

Defining an ageing-related pathology, disease or syndrome: International Consensus Statement.

Journal article

Short E. et al, (2025), Geroscience, 47, 1713 - 1720

UKEV forum 2024: The UK Society for Extracellular Vesicle annual meeting - bridging innovation and impact.

Conference paper

Jackson HK. et al, (2025), Extracell Vesicles Circ Nucl Acids, 6, 516 - 521

UKEV Forum 2024: the UK Society for Extracellular Vesicles Annual Meeting - Abstracts.

Journal article

Jackson HK. et al, (2025), Extracell Vesicles Circ Nucl Acids, 6, 742 - 790

The isolation of VCAM-1+ endothelial cell-derived extracellular vesicles using microfluidics.

Journal article

Akbar N. et al, (2024), Extracell Vesicles Circ Nucl Acids, 5, 83 - 94