Richard Williams

Associate Professor

Richard Williams has worked at the Kennedy Institute of Rheumatology since 1989 and was a Senior Lecturer (2007-2011) and then Reader (2011-2012) at Imperial College London before joining the University of Oxford.

He is also a Visiting Lecturer at Queen Mary University of London and the London School of Hygiene and Tropical Medicine and was recently appointed as an Editor of Frontiers in Immunology.

He has established an internationally recognised reputation in translational research and his early studies were instrumental in the development of TNF blocking biologics.

He has carried out numerous projects with British and overseas industrial partners, including Merck, Pfizer, GSK, UCB, Schering, Celgene and J&J and has led an MRC DPFS project on rheumatoid arthritis.

Recent publications

Pharmacological modulation of T cell immunity results in long-term remission of autoimmune arthritis.
Journal article

Huang Y-S. et al, (2021), Proc Natl Acad Sci U S A, 118
TNFα inhibitors reduce bone loss in rheumatoid arthritis independent of clinical response by reducing osteoclast precursors and IL-20
Journal article

Al-Bogami M. et al, (2020), Rheumatology
IDO activation, inflammation and musculoskeletal disease
Journal article

Ogbechi J. et al, (2020), Experimental Gerontology, 131, 110820 - 110820
TNF receptor 2 signaling prevents DNA methylation at the Foxp3 promoter and prevents pathogenic conversion of regulatory T cells.
Journal article

Tseng W-Y. et al, (2019), Proc Natl Acad Sci U S A
cIAP1/2 inhibition synergizes with TNF inhibition in autoimmunity by down-regulating IL-17A and inducing Treg cells
Journal article

WILLIAMS R. et al, (2019), Science Advances

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