Prof Timothy SC Hinks
+44 1865 (2)20885
Room 7400A, Level 7 NDM, John Radcliffe Hospital, Headley Way, Oxford, OX3 9DU, UK
The Oxford severe asthma MDT and research nurse team
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Prof Timothy SC Hinks
BMBCh MA (Cantab) MRCP PhD
Wellcome Trust Fellow & Honorary Consultant
- Associate Professor and Wellcome Trust Career Development Fellow, Respiratory Immunology, Nuffield Dept of Medicine
- NIHR Oxford Biomedical Research Centre Senior Research Fellow
- Honorary Consultant, Oxford Special Airway Service, Respiratory Medicine, Oxford University Hospitals NHS Trust
Investigating immune responses in asthma and lung infections
My group investigate the immunopathogenesis of airway diseases and pulmonary infections. We have a specific focus on the roles of novel T cell subsets in the mucosal immunology of the airways, particularly in driving inflammation in asthma and during chronic airways infection.
After a background in translational research in T cell immunodiagnostics in tuberculosis I have been funded by fellowships from the Wellcome Trust, Academy of Medical Sciences and National Institute of Health Research to study novel T cell subsets in the airways in human asthma and more recently the roles of mucosal associated invariant T (MAIT) cells in ex vivo and murine models of infection with Haemophilus influenzae, Legionella and Influenza virus.
Our goal is to better understand the immune responses which protect us from lung infections or can drive airways inflammation, to help develop new treatments to prevent exacerbations of lung diseases and to accelerate the development of improved vaccines.
Currently we have a position open for a postdoc - focusing on defining the mechanisms by which bacteria subvert mucosal immunity to establish a niche within the airways. If you are interested, please get in touch by email to find out more.
Innate T cells in airways disease
Airway epithelial cell biology
Volunteer as a research participant
If you would be interested in volunteering in our research studies, either as a healthy control or as someone with asthma, fill in this form and we can tell you more
Our research bronchoscopies
Find out what its like to volunteer for one of our research bronchoscopy studies
The full length video - watch research volunteer Tom undergo a bronschoscopy
Severely asthma - Peter's story
Listen to Peter's experience of living with severe asthma, and the transformative effects of new treatments
Epithelial immune activation and intracellular invasion by non-typeable Haemophilus influenzae
Brown MA. et al, (2023), Frontiers in Cellular and Infection Microbiology, 13
Non-typeable Haemophilus influenzae airways infection: the next treatable trait in asthma?
HINKS T. et al, (2022), European Respiratory Review
Longitudinal changes in sputum and blood inflammatory mediators during FeNO suppression testing
Couillard S. et al, (2022), Thorax
Sub-stratification of type-2 high airway disease for therapeutic decision-making: a ‘bomb' (blood eosinophils) meets ‘magnet' (FeNO) framework
Couillard Castonguay S. et al, (2022), Respirology
From spirometry to spatial omics in pursuit of asthma endotypes
HINKS T., (2022), Clinical and Translational Medicine