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The Society for Immunotherapy of Cancer (SITC) has honoured Dr Ignacio (Nacho) Melero, Professor of Immunotherapy at NDM's Centre for Immuno-Oncology at Oxford, for his pioneering research transforming cancer treatment through immunotherapy.

Ignacio Melero receiving his award
Dr Ignacio (Nacho) Melero inducted into the 2025 Class of Fellows of the Academy of Immuno-Oncology (FAIO). Pictured with his nominator, Kim A. Margolin, MD, FASCO, Saint John's Cancer Institute.

Dr Melero, who holds a joint appointment at the Centre for Immuno-Oncology, Nuffield Department of Medicine, University of Oxford, and Clinica y Cima Universidad de Navarra, has been named a member of the SITC Academy in recognition of his decades-long contribution to the field of cancer immunotherapy. The Academy brings together leaders in immuno-oncology from across the globe, representing more than 35 medical specialties and over 4,500 members in 63 countries.

SITC highlighted Dr Melero's transformative research in the treatment of hepatocellular carcinoma, the most common form of liver cancer. His work has been instrumental in improving survival outcomes for patients with inoperable tumours through immunotherapy-based approaches.

A key focus of Dr Melero's research has been the development of intratumoural immunotherapies and the selective stimulation of the 4-1BB protein, which enhances T-cell proliferation, survival and tumour-killing efficacy. Appointed Kidani Professor of Immuno-Oncology at Oxford in 2022, Dr Melero continues to lead internationally collaborative research into new therapeutic techniques.

Reflecting on the recognition, Dr Ignacio Melero said: "I feel deeply honoured to receive this recognition. What matters most to me is how immunotherapy changes the outlook for people who previously had no options. Every therapeutic advance brings us closer to the day when cancer becomes a controllable, and perhaps even curable, disease."

Read the full story on the Nuffield Department of Medicine website