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RDM launches new metabolism cross-cutting research theme

On Monday 10 June, more than 50 members of RDM met to kick off the ‘Metabolism in Molecular Medicine’ cross-cutting research theme.

Researchers find dramatic acceleration of SARS CoV2 viral clearance rates

Running continuously since Sept 2021, the PLATCOV trial at NDM's Mahidol Oxford Tropical Medicine Research Unit has randomised over 1700 patients presenting with COVID-19 infections. Work by PLATCOV’s Dr Phrutsamon Wongnak published in the Lancet Infectious Diseases has shown that rates of oropharyngeal viral clearance have accelerated dramatically since the trial started: A SARS CoV2 viral clearance half-life in untreated patients of around 16 hours In Sept 2021 had reduced to around 9 hours by Oct 2023. The results highlight the importance of pharmacometric platform trials like PLATCOV, so that we are prepared for the next pandemic.

Thanks for the Memories performance at the Royal Northern College of Music

Thanks for the Memories, Wellcome-funded public engagement project led by Prof. Paul Klenerman and composer Dr Zakiya Leeming, hosted an innovative evening of music and science at the Royal Northern College of Music in early May.

Dr Yiqi Zhao wins the inaugural Peter Medawar Prize for Immunology

The 2024 prize was awarded to Dr Yiqi Zhao (Dunn School) for her outstanding contribution to understanding innate immunity and viral evasion, and wider contributions to the immunology community.

New study maps the crucial factors in inflammation control

A Cell Reports study from the Target Discovery Institute and CAMS Oxford Institute provides an intricate time-resolved molecular map of different phases of NLRP3 inflammasome activation and unveils ubiquitin C-terminal hydrolase 1 (UCH-L1) as a modulator of NLRP3 inflammasome assembly and IL-1β production.

NDM-CGHR Director announcement

Professor Susanna Dunachie has been appointed to the new role of Director of the NDM Centre for Global Health Research

Ground-breaking study reveals how COVID-19 vaccines prevent severe disease

A landmark study by scientists at the University of Oxford, has unveiled crucial insights into the way that COVID-19 vaccines mitigate severe illness in those who have been vaccinated.

Nature Nanotechnology study introduces new and improved version of all-in-one coronavirus vaccine

CAMS Oxford Institute researchers publish an improved version of a novel all-in-one vaccine against coronavirus threats in Nature Nanotechnology.

Researchers discover how immune cells hunt down cancer around the body

Scientists have discovered the key features of immune B cells which make them successful at targeting tumours - including when cancer has spread to a different part of the body.

Dr Ashwin Jainarayanan selected for 2024 Schmidt Science Fellow program

Dr Ashwin Jainarayanan has been selected to become a 2024 Schmidt Science Fellow – an honour bestowed on only 32 exceptional early career researchers worldwide. The 2024 Fellows, nominated by 26 of the world’s leading institutions across North America, Europe, and Asia, were chosen for their potential to drive sector-wide change by pursuing ambitious interdisciplinary science projects.

New study to improve vaccines and therapeutics development

NDM

A first-of-its-kind study led by the University of Oxford has successfully investigated human immunity against COVID-19 in people who already have antibodies against it.

Unveiling of Medawar Nobel Prize medal

On Thursday 25th April 2024, the Oxford immunology community celebrated the kind donation of Sir Peter Medawar’s Nobel Prize medal to the University.

Immunology at the MRC WIMM

WIMM

For International Day of Immunology 2024, three scientists from the MRC Translational Immune Discovery Unit speak about their research.

The potential of the R21/Matrix vaccine to redefine malaria prevention

Researchers from the Jenner Institute at NDM will present new exciting data on the R21/Matrix-M malaria vaccine during the 8th Pan-African Malaria Conference, in collaboration with the Rwandan Ministry of Health and the Rwanda Biomedical Centre.

British Heart Foundation Programme grant will explore the molecular immunology of heart and vessel disease

A new programme of research led by Professor Claudia Monaco and funded by the British Heart Foundation aims to unpick the inflammatory processes behind cardiovascular disease so that immune-targeted therapies may be developed in future.

New trial using skin patches as an ‘early warning system’ to spot lung transplant rejection

A new trial, SENTINEL, is set to investigate if skin patches can be used as an early warning system to identify if lung transplants are being rejected, so treatment can begin sooner, reducing the chance of longer lasting organ damage.

Serum Institute of India and University of Oxford strike landmark licensing agreement for Meningitis-B vaccine

Serum Institute of India Pvt. Ltd (SIIPL), in collaboration with the University of Oxford, is developing a novel solution for Men-B disease, advancing global accessibility to life-saving vaccines.

Aerosol human infection model gives hope for TB vaccine development

University of Oxford researchers have for the first time established a controlled human infection model for tuberculosis (TB) that infects people via the lungs – the way TB enters the body.

New study reveals how T cells gain and maintain tolerance to gut bacteria

The immune system in the intestine maintains a careful balance, tolerating our long-term resident (commensal) gut bacteria while defending against invading pathogens. Under certain circumstances, dysregulation of our intestinal immune response to commensal and pathogenic microbes can drive inflammatory disease.

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