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Publications

cGAS-STING signalling in cancer: striking a balance with chromosomal instability.

Beernaert B. and Parkes EE., (2023), Biochem Soc Trans

A non-coding RNA balancing act: miR-346-induced DNA damage is limited by the long non-coding RNA NORAD in prostate cancer

Fletcher CE. et al, (2022), Molecular Cancer, 21, 82 - 82

Activation of a cGAS-STING-mediated immune response predicts response to neoadjuvant chemotherapy in early breast cancer.

Parkes EE. et al, (2022), Br J Cancer, 126, 247 - 258

When breaks get hot: inflammatory signaling in BRCA1/2-mutant cancers.

van Vugt MATM. and Parkes EE., (2022), Trends Cancer

The tumor microenvironment and immune responses in prostate cancer patients.

Kwon JTW. et al, (2021), Endocr Relat Cancer, 28, T95 - T107

Phase I, first-in-human trial evaluating BI 1387446 (STING agonist) alone and in combination with ezabenlimab (BI 754091; anti-PD-1) in solid tumors.

Harrington K. et al, (2021), CANCER RESEARCH, 81

The clinical and molecular significance associated with STING signaling in breast cancer.

Parkes EE. et al, (2021), NPJ Breast Cancer, 7

Development of Immunotherapy Combination Strategies in Cancer.

Yap TA. et al, (2021), Cancer Discov, 11, 1368 - 1397

Metastasis and Immune Evasion from Extracellular cGAMP Hydrolysis.

Li J. et al, (2021), Cancer Discov, 11, 1212 - 1227

Circulating biomarkers and outcomes from a randomised phase 2 trial of gemcitabine versus capecitabine-based chemoradiotherapy for pancreatic cancer.

Willenbrock F. et al, (2021), Br J Cancer, 124, 581 - 586

The clinical and molecular significance associated with STING signaling in estrogen receptor-positive early breast cancer

Parkes EE. et al, (2020)

DNA Repair Deficiency in Breast Cancer: Opportunities for Immunotherapy

Gilmore E. et al, (2019), JOURNAL OF ONCOLOGY, 2019

Review of applications of high-throughput sequencing in personalized medicine: barriers and facilitators of future progress in research and clinical application

Lightbody G. et al, (2019), BRIEFINGS IN BIOINFORMATICS, 20, 1795 - 1811

Topoisomerase II inhibitors induce cGAS-STING dependent inflammation resulting in cytokine induction and immune checkpoint activation

Wilkinson RDA. et al, (2019)

Clinical Application of Poly(ADP-Ribose) Polymerase Inhibitors in High-Grade Serous Ovarian Cancer

Parkes EE. and Kennedy RD., (2016), ONCOLOGIST, 21, 586 - 593

Clinical Tumor Staging of Adenocarcinoma of the Esophagus and Esophagogastric Junction

Turkington RC. et al, (2015), JOURNAL OF CLINICAL ONCOLOGY, 33, 1088 - +

Include forthcoming?