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Publications

MHC class II antigen presentation by intestinal epithelial cells fine-tunes bacteria-reactive CD4 T cell responses.

Heuberger CE. et al, (2023), Mucosal Immunol

Adipocyte autophagy limits gut inflammation by controlling oxylipin and IL-10.

Richter FC. et al, (2023), EMBO J

A conserved population of MHC II-restricted, innate-like, commensal-reactive T cells in the gut of humans and mice.

Hackstein C-P. et al, (2022), Nat Commun, 13

A viral cocktail calms gut inflammation.

Bertocchi A. and Powrie F., (2022), Nature, 612, 220 - 221

Hermansky-Pudlak syndrome type 1 causes impaired anti-microbial immunity and inflammation due to dysregulated immunometabolism.

Cavounidis A. et al, (2022), Mucosal Immunol

Author Correction: Somatic mosaicism and common genetic variation contribute to the risk of very-early-onset inflammatory bowel disease.

Serra EG. et al, (2022), Nat Commun, 13

Cross-tissue, single-cell stromal atlas identifies shared pathological fibroblast phenotypes in four chronic inflammatory diseases.

Korsunsky I. et al, (2022), Med (N Y)

Genetic and environmental factors shape the host response to Helicobacter hepaticus: insights into IBD pathogenesis.

Jeffery R. et al, (2021), Curr Opin Microbiol, 65, 145 - 155

IL-1-driven stromal-neutrophil interactions define a subset of patients with inflammatory bowel disease that does not respond to therapies.

Friedrich M. et al, (2021), Nat Med, 27, 1970 - 1981

Adipocyte autophagy limits gut inflammation by controlling oxylipin levels

Richter FC. et al, (2021)

Role of autophagy in immune aging

Richter F. et al, (2021), EUROPEAN JOURNAL OF IMMUNOLOGY, 51, 10 - 10

Deconvolution of monocyte responses in inflammatory bowel disease reveals an IL-1 cytokine network that regulates IL-23 in genetic and acquired IL-10 resistance.

Aschenbrenner D. et al, (2021), Gut, 70, 1023 - 1036

Gut microbiota: sculptors of the intestinal stem cell niche in health and inflammatory bowel disease.

Markandey M. et al, (2021), Gut Microbes, 13

Tissue-dependent transcriptional and bacterial associations in primary sclerosing cholangitis-associated inflammatory bowel disease.

Ilott NE. et al, (2021), Wellcome Open Res, 6

Host-microbiota maladaptation in colorectal cancer.

Janney A. et al, (2020), Nature, 585, 509 - 517

IRF5 guides monocytes toward an inflammatory CD11c+ macrophage phenotype and promotes intestinal inflammation.

Corbin AL. et al, (2020), Sci Immunol, 5

The interleukin 22 pathway interacts with mutant KRAS to promote poor prognosis in colon cancer.

McCuaig S. et al, (2020), Clinical cancer research : an official journal of the American Association for Cancer Research, clincanres.1086.2019 - clincanres.1086.2019

Loss of IL-10 signaling in macrophages limits bacterial killing driven by prostaglandin E2.

Mukhopadhyay S. et al, (2020), J Exp Med, 217

High-throughput phenotyping reveals expansive genetic and structural underpinnings of immune variation.

Abeler-Dörner L. et al, (2020), Nature immunology, 21, 86 - 100

Very Early Onset Inflammatory Bowel Disease: A Clinical Approach With a Focus on the Role of Genetics and Underlying Immune Deficiencies.

Ouahed J. et al, (2019), Inflamm Bowel Dis

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