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Publications

The crystal structure of human forkhead box N1 in complex with DNA reveals the structural basis for forkhead box family specificity.

Newman JA. et al, (2019), J Biol Chem

Comment on "Identification of an Intronic Regulatory Element Necessary for Tissue-Specific Expression of Foxn1 in Thymic Epithelial Cells"

Handel AE. and Holländer GA., (2019), Journal of immunology (Baltimore, Md. : 1950), 203

Biologically indeterminate yet ordered promiscuous gene expression in single medullary thymic epithelial cells

Dhalla F. et al, (2019), The EMBO Journal

Florescent timer protein as a molecular stop watch during embryonic thymic epithelial cell development

Cheuk S. et al, (2019), EUROPEAN JOURNAL OF IMMUNOLOGY, 49, 355 - 356

Gene Modification and Three-Dimensional Scaffolds as Novel Tools to Allow the Use of Postnatal Thymic Epithelial Cells for Thymus Regeneration Approaches.

Bortolomai I. et al, (2019), Stem Cells Transl Med

Keratinocyte growth factor impairs human thymic recovery from lymphopenia

Coles AJ. et al, (2019), JCI Insight

Disruption of Coronin 1 Signaling in T Cells Promotes Allograft Tolerance while Maintaining Anti-Pathogen Immunity.

Jayachandran R. et al, (2019), Immunity, 50, 152 - 165.e8

Maturing Human CD127+CCR7+PDL1+Dendritic Cells Express AIRE in the Absence of Tissue Restricted Antigens

Fergusson JR. et al, (2019), FRONTIERS IN IMMUNOLOGY, 9

Engineering Regenerative Thymic Tissues to Restore Long-Term T Cell Lymphopoiesis

Gai H. et al, (2018), BLOOD, 132

The role of thymic tolerance in CNS autoimmune disease

HANDEL AE. et al, (2018), Nature Reviews Neurology

Thymic epithelial cell support of thymopoiesis does not require Klotho

Xing Y. et al, (2018), Journal of Immunology

The structural basis for forkhead box family specificity revealed by the crystal structure of human FOXN1 in complex with DNA

Newman JA. et al, (2018)

Comprehensively Profiling the Chromatin Architecture of Tissue Restricted Antigen Expression in Thymic Epithelial Cells Over Development

HANDEL AE. et al, (2018), Frontiers in Immunology, 9

Retinoic Acid Signaling in Thymic Epithelial Cells Regulates Thymopoiesis.

Wendland K. et al, (2018), J Immunol, 201, 524 - 532

Insufficiency in the Reporting of CAR-T Manufacturing Protocols - A Systematic Review and Mixed-Methods Analysis

Pettitt D. et al, (2018), Future Science OA

Despite high levels of expression in thymic epithelial cells, miR-181a1 and miR-181b1 are not required for thymic development.

Stefanski HE. et al, (2018), PLoS One, 13

CAR-T: A Systematic Review and Mixed-Methods Analysis of the Clinical Trial Landscape

Pettitt D. et al, (2017), Molecular Therapy

Cadherin 17 mutation associated with leaky severe combined immune deficiency is corrected by HSCT.

Smith AR. et al, (2017), Blood advances, 1, 2083 - 2087

A Critical Epithelial Survival Axis Regulated by MCL-1 Maintains Thymic Function in Mice

Jain R. et al, (2017), Blood

In situ functional dissection of RNA cis-regulatory elements by multiplex CRISPR-Cas9 genome engineering

Fulga TA. et al, (2017), Nature Communications

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