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Fully reduced HMGB1 accelerates the regeneration of multiple tissues by transitioning stem cells to G(alert)

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Lee G. et al, (2018), Proceedings of the National Academy of Sciences

Developments in therapy with monoclonal antibodies and related proteins.

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Shepard HM. et al, (2017), Clin Med (Lond), 17, 220 - 232

Anti-TNF Therapy.

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Udalova I. et al, (2016), Microbiol Spectr, 4

Macrophage heterogeneity in the context of rheumatic diseases

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udalova I. et al, (2016), Nature Reviews Rheumatology

Indoleamine 2,3-dioxygenase-1 is protective in atherosclerosis and its metabolites provide new opportunities for drug development.

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Cole JE. et al, (2015), Proc Natl Acad Sci U S A, 112, 13033 - 13038

Towards an understanding of the role of DNA methylation in rheumatoid arthritis: therapeutic and diagnostic implications.

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Cribbs A. et al, (2015), Ther Adv Musculoskelet Dis, 7, 206 - 219

Selective inhibition of TNFR1 reduces osteoclast numbers and is differentiated from anti-TNF in a LPS-driven model of inflammatory bone loss.

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Espirito Santo AI. et al, (2015), Biochem Biophys Res Commun, 464, 1145 - 1150

IRF5 controls both acute and chronic inflammation

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Weiss M. et al, (2015), Proceedings of the National Academy of Sciences of the United States of America, 112, 11001 - 11006

IRF5 controls both acute and chronic inflammation.

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Weiss M. et al, (2015), Proc Natl Acad Sci U S A, 112, 11001 - 11006

Perspectives From Masters in Rheumatology and Autoimmunity: Can We Get Closer to a Cure for Rheumatoid Arthritis?

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Feldmann M. and Maini RN., (2015), Arthritis Rheumatol, 67, 2283 - 2291

Preclinical target validation using patient-derived cells.

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Edwards AM. et al, (2015), Nat Rev Drug Discov, 14, 149 - 150

Anti-TNF therapy: past, present and future.

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Monaco C. et al, (2015), Int Immunol, 27, 55 - 62

Low-dose TNF augments fracture healing in normal and osteoporotic bone by up-regulating the innate immune response

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Chan JK. et al, (2015), EMBO Molecular Medicine, 7, 547 - 561

Design and optimisation of bioactive cyclic peptides: generation of a down-regulator of TNF secretion.

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New R. et al, (2014), Molecules, 19, 21529 - 21540

Discovery and Development of Anti-TNF Therapy: Pillar of a Therapeutic Revolution. Pillar of a Therapeutic Revolution.


Feldmann M., (2014), Molecular Biology of B Cells: Second Edition, 541 - 547

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