CD4+ tissue-resident memory Th17 cells are a major source of IL-17A in Spondyloarthritis synovial tissue.
Liu F. et al, (2025), Ann Rheum Dis
Inflammatory disease microbiomes share a functional pathogenicity predicted by C-reactive protein.
Britton GJ. et al, (2025), bioRxiv
Transcriptomic effects of methotrexate on natural killer cells in psoriatic arthritis
Tucker LJ. et al, (2025), RHEUMATOLOGY, 64
HLA-B27 and spondyloarthritis: at the crossroads of innate and adaptive immunity.
Navid F. et al, (2024), Nat Rev Rheumatol
Chimeric antigens displaying GPR65 extracellular loops on a soluble scaffold enabled the discovery of antibodies, which recognized native receptor.
Barrett J. et al, (2024), Bioengineered, 15
Pathogenic T-cell clones in axial spondyloarthritis: what is the evidence?
Penkava F. et al, (2024), Rheumatology (Oxford), 63, ii4 - ii6
Mucosal signatures of pathogenic T cells in HLA-B*27+ anterior uveitis and axial spondyloarthritis.
Paley MA. et al, (2024), JCI Insight
Elevated type-17 cytokines are present in Axial Spondyloarthritis stool
BOWNESS P. and BROUGH I., (2024), Discovery Immunology
Increased interleukin-26 in the peripheral joints of patients with axial spondyloarthritis and psoriatic arthritis, co-localizing with CD68-positive synoviocytes.
Hammitzsch A. et al, (2024), Front Immunol, 15
Alterations in the gut microbiome implicate key taxa and metabolic pathways across inflammatory arthritis phenotypes.
Thompson KN. et al, (2023), Sci Transl Med, 15
Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis
Brown AC. et al, (2023), Cell Genomics, 3
Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides.
Yang X. et al, (2022), Nature
Constructing custom-made radiotranscriptomic signatures of vascular inflammation from routine CT angiograms: a prospective outcomes validation study in COVID-19.
Kotanidis CP. et al, (2022), Lancet Digit Health, 4, e705 - e716
A blood atlas of COVID-19 defines hallmarks of disease severity and specificity.
COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium. Electronic address: julian.knight@well.ox.ac.uk None. and COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium None., (2022), Cell, 185, 916 - 938.e58
An immunodominant NP105-113-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease.
Peng Y. et al, (2022), Nat Immunol, 23, 50 - 61
FUNCTIONAL GENOMICS INVESTIGATION OF THE ANKYLOSING SPONDYLITIS ASSOCIATED LOCUS RUNX3
Cohen C. et al, (2022), ANNALS OF THE RHEUMATIC DISEASES, 81, 231 - 231