Proximity proteomics reveals UCH-L1 as an essential regulator of NLRP3-mediated IL-1β production in human macrophages and microglia.
Liang Z. et al, (2024), Cell Rep, 43
Tracking in situ checkpoint inhibitor-bound target T cells in patients with checkpoint-induced colitis.
Gupta T. et al, (2024), Cancer Cell, 42, 797 - 814.e15
Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity.
Hamid MHBA. et al, (2024), Nat Immunol, 25, 834 - 846
TCR ligand potency differentially impacts PD-1 inhibitory effects on diverse signaling pathways.
Chan W. et al, (2023), J Exp Med, 220
A robust deep learning workflow to predict CD8 + T-cell epitopes.
Lee CH. et al, (2023), Genome Med, 15
A cell-topography based mechanism for ligand discrimination by the T-cell receptor
Fernandes RA. et al, (2017)