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Publications

Structural and non-coding variants increase the diagnostic yield of clinical whole genome sequencing for rare diseases.

Pagnamenta AT. et al, (2023), Genome Med, 15

Probing long COVID through a proteomic lens: a comprehensive two-year longitudinal cohort study of hospitalised survivors.

Gu X. et al, (2023), EBioMedicine, 98

HBV001: Phase I study evaluating the safety and immunogenicity of the therapeutic vaccine ChAdOx1-HBV.

Cargill T. et al, (2023), JHEP Rep, 5

Long COVID research: an update from the PHOSP-COVID Scientific Summit.

Brightling CE. et al, (2023), Lancet Respir Med, 11, e93 - e94

Multiorgan MRI findings after hospitalisation with COVID-19 in the UK (C-MORE): a prospective, multicentre, observational cohort study.

C-MORE/PHOSP-COVID Collaborative Group None., (2023), Lancet Respir Med, 11, 1003 - 1019

Emulsion and liposome-based adjuvanted R21 vaccine formulations mediate protection against malaria through distinct immune mechanisms.

Reinke S. et al, (2023), Cell Rep Med

Interferon-γ couples CD8+ T cell avidity and differentiation during infection

Uhl LFK. et al, (2023), Nature Communications

Targeting mitotic regulators in cancer as a strategy to enhance immune recognition.

Gregorczyk M. and Parkes EE., (2023), DNA Repair (Amst), 132

Type I interferons drive MAIT cell functions against bacterial pneumonia.

López-Rodríguez JC. et al, (2023), J Exp Med, 220

SARS-CoV-2 mutations affect antigen processing by the proteasome to alter CD8+ T cell responses.

Wellington D. et al, (2023), Heliyon, 9

Clinical trial protocol for PanDox: a phase I study of targeted chemotherapy delivery to non-resectable primary pancreatic tumours using thermosensitive liposomal doxorubicin (ThermoDox®) and focused ultrasound.

Spiers L. et al, (2023), BMC Cancer, 23

Vaccine-induced CD8+ T cells are key to protection from SARS-CoV-2.

Antoun E. et al, (2023), Nat Immunol

The molecular reach of antibodies determines their SARS-CoV-2 neutralisation potency

Huhn A. et al, (2023)

Engineering immunosuppressive drug-resistant armored (IDRA) SARS-CoV-2 T cells for cell therapy.

Chen Q. et al, (2023), Cell Mol Immunol

Aging unconventionally: γδ T cells, iNKT cells, and MAIT cells in aging.

Kurioka A. and Klenerman P., (2023), Semin Immunol, 69

Single-cell diversity and functional plasticity of human MAIT cells.

(2023), Nat Immunol, 24, 1409 - 1410

Single-cell immune multi-omics and repertoire analyses in pancreatic ductal adenocarcinoma reveal differential immunosuppressive mechanisms within different tumour microenvironments

Sivakumar S. et al, (2023)

Omicron infection following vaccination enhances a broad spectrum of immune responses dependent on infection history.

Hornsby H. et al, (2023), Nat Commun, 14

Single-cell analysis of human MAIT cell transcriptional, functional and clonal diversity

GARNER LC. et al, (2023), Nature Immunology

STAT3/LKB1 controls metastatic prostate cancer by regulating mTORC1/CREB pathway.

Pencik J. et al, (2023), Mol Cancer, 22

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