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Publications

Targeting ER α-glucosidase I with a single-dose iminosugar treatment protects against lethal influenza and dengue virus infections

Warfield K. et al, (2020), Journal of Medicinal Chemistry

Structures of SALSA/DMBT1 SRCR domains reveal the conserved ligand-binding mechanism of the ancient SRCR-fold

REICHHARDT M. et al, (2020), Life Science Alliance

The substrate specificity switch FlhB assembles onto the export gate to regulate type three secretion

Kuhlen L. et al, (2020), Nature Communications

The guidance receptor plexin D1 is a mechanosensor in endothelial cells.

Mehta V. et al, (2020), Nature

LAX28 is required for stable assembly of the inner dynein arm f/l1 and tether/tether head complex in Leishmania flagella.

Beneke T. et al, (2020), J Cell Sci

H3K4 demethylase JARID1A directly interacts with haematopoietic transcription factor GATA1 in erythroid cells through its second PHD domai

PORCHER C. et al, (2020), Royal Society Open Science

Structure and dynamics of the E. coli chemotaxis core signaling complex by cryo-electron tomography and molecular simulations

Cassidy CK. et al, (2020), Communications Biology, 3

A key region of molecular specificity orchestrates unique ephrin-B1 utilization by Cedar virus.

Pryce R. et al, (2020), Life Sci Alliance, 3

Design of a basigin-mimicking inhibitor targeting the malaria invasion protein RH5.

Warszawski S. et al, (2020), Proteins, 88, 187 - 195

Structure and mechanism of bactericidal mammalian perforin-2, an ancient agent of innate immunity.

Ni T. et al, (2020), Sci Adv, 6

Unraveling virus relationships by structure-based phylogenetic classification.

Ng WM. et al, (2020), Virus Evol, 6

In Situ Structure of an Intact Lipopolysaccharide-Bound Bacterial Surface Layer

von Kügelgen A. et al, (2019), Cell

Structural characterisation of melatonin as an inhibitor of the Wnt deacylase Notum.

Zhao Y. et al, (2019), J Pineal Res

An inhibitor of complement C5 provides structural insights into activation.

Reichhardt MP. et al, (2019), Proc Natl Acad Sci U S A

Cell guidance ligands, receptors and complexes - orchestrating signalling in time and space.

Rozbesky D. and Jones EY., (2019), Curr Opin Struct Biol, 61, 79 - 85

A structural basis for antibody-mediated neutralization of Nipah virus reveals a site of vulnerability at the fusion glycoprotein apex.

Avanzato VA. et al, (2019), Proc Natl Acad Sci U S A, 116, 25057 - 25067

The evolutionary dynamics of Oropouche Virus in South America.

Gutierrez B. et al, (2019), J Virol

A generic cell surface ligand system for studying cell-cell recognition.

Denham EM. et al, (2019), PLoS Biol, 17

AutoCLEM: An Automated Workflow for Correlative Live-Cell Fluorescence Microscopy and Cryo-Electron Tomography

Fu X. et al, (2019), Scientific Reports, 9

The complex of Plasmodium falciparum falcipain-2 protease with an (E)-chalcone-based inhibitor highlights a novel small molecule binding site.

Machin J. et al, (2019), Malaria Journal

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