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<jats:title>Key Points</jats:title> <jats:p>FL-infiltrating stromal cells overexpress CXCL12, which triggers FL B-cell migration, adhesion, and activation. Polarization into CXCL12hi stroma involves IL-4+ TFH cells, unlike malignant B cells, revealing an indirect protumoral activity of FL-TFH cells.</jats:p>

Original publication

DOI

10.1182/blood-2016-08-737239

Type

Journal article

Journal

Blood

Publisher

American Society of Hematology

Publication Date

04/05/2017

Volume

129

Pages

2507 - 2518