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Following the successful determination of the molecular genetics of single-gene disorders, attention has not surprisingly turned to complex genetic disorders. However, preliminary experience suggests that unravelling the genetic component of common inflammatory disorders, such as rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus, might be a harder nut to crack.

Type

Journal article

Journal

Curr Opin Pharmacol

Publication Date

06/2003

Volume

3

Pages

280 - 285

Keywords

Arthritis, Rheumatoid, Cytokines, HLA Antigens, Hormones, Humans, Polymorphism, Genetic, Tumor Necrosis Factor-alpha