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OBJECTIVE: To assess the genetic association between secretor status and ankylosing spondylitis (AS). METHODS: A restriction digest method for determining secretor status was developed; 166 patients with AS and 216 healthy British white controls were typed for secretor status using this method. RESULTS: The frequency of nonsecretors among patients with AS (47/166, 28%) was not significantly different from controls (72/216, 33%). CONCLUSION: Secretor status does not influence susceptibility to AS.


Journal article


J Rheumatol

Publication Date





318 - 319


Cohort Studies, Fucosyltransferases, Humans, Immunity, Mucosal, Spondylitis, Ankylosing