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Efficient in vitro and in vivo systems are now in place to study the role of viral proteins in replication and/or transcription, the regulation of these processes, polyadenylation of viral mRNAs, the viral promoter structures, or the significance of noncoding regions for virus replication. In this chapter, we review the status of current knowledge of the orthomyxovirus RNA synthesis.


Journal article


Curr Top Microbiol Immunol

Publication Date





121 - 143


DNA-Directed RNA Polymerases, Influenza A virus, Influenza B virus, Influenzavirus C, Orthomyxoviridae, Polyadenylation, RNA, Messenger, RNA, Viral, Thogotovirus, Transcription, Genetic, Viral Proteins, Virus Replication